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study association level lipid population effect polymorphism analysis disease patient allele rotterdam lipase plasma cholesterol genotype hepatic linkage haplotype 10-1 family chromosome genome-wide table factor result region variant stroke model treatment cohort p-value blood ratio subject hdl levels rotterdam study chapter individual lipid levels lipoprotein score analyses genet netherland protein apolipoprotein j lipid res interaction disc area plasma lipids atherosclerosi activity apoa 5 gene treatment bene fit variation usf 1 difference hepatic lipase gene hypertension sample hepatic lipase hyperlipidemia body mass index group serum tg /hdl ratio number 1.00 erasmu participant perindopril figure pressure promoter trait method gly 460trp polymorphism diabetes
10 Most Recent Publications
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A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14
(Letter To Editor)
Solouki, A.M. Verhoeven, V.J.M. Czudowska, M.A. Kuijpers, R.W.A.M. Amin, N. Struchalin, M.V. Aulchenko, Y.S. Rij, G. van Riemslag, F.C.C. Young, T.L. Mackey, D.A. Spector, T.D. Duijn, C.M. van Gorgels, T.G.M.F. Willemse-Assink, J.J.M. Isaacs, A.J. Kramer, R. Swagemakers, S.M.A. Bergen, A.A.B Oosterhout, A.A.L.J. van Oostra, B.A. Rivadeneira Ramirez, F. Uitterlinden, A.G. Verkerk, J.H.M. Hofman, A. Jong, P.T.V.M. de Hammond, C.J. Vingerling, J.R. Klaver, C.C.W. Ikram, M.K. Hysi, P.G. Despriet, D.D.G. Koolwijk, L.M.E. van Ho, L. Ramdas, W.D. |
2010-09-01
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A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14
(Letter To Editor)
Solouki, A.M. Verhoeven, V.J.M. Czudowska, M.A. Kuijpers, R.W.A.M. Amin, N. Struchalin, M.V. Aulchenko, Y.S. Rij, G. van Riemslag, F.C.C. Young, T.L. Mackey, D.A. Spector, T.D. Duijn, C.M. van Gorgels, T.G.M.F. Willemse-Assink, J.J.M. Isaacs, A.J. Kramer, R. Swagemakers, S.M.A. Bergen, A.A.B Oosterhout, A.A.L.J. van Oostra, B.A. Rivadeneira Ramirez, F. Uitterlinden, A.G. Verkerk, J.H.M. Hofman, A. Jong, P.T.V.M. de Hammond, C.J. Vingerling, J.R. Klaver, C.C.W. Ikram, M.K. Hysi, P.G. Despriet, D.D.G. Koolwijk, L.M.E. van Ho, L. Ramdas, W.D. |
2010-09-01
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Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease
(Article)
Brugts, J.J. Isaacs, A.J. MacMahon, S. Fox, K.M. Ferrari, R. Witteman, J.C.M. Danser, A.H.J. Simoons, M.L. Maat, M.P.M. de Boersma, E.R. Duijn, C.M. van Uitterlinden, A.G. Remme, W.J. Bertrand, M.E. Ninomiya, T. Ceconi, C. Chalmers, J. |
2010-08-01
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A genome-wide association study of optic disc parameters
(Article)
Ramdas, W.D. Koolwijk, L.M.E. van Hofman, A. Rivadeneira Ramirez, F. Oostra, B.A. Uitterlinden, A.G. Hysi, P.G. Hammond, C.J. Lemij, H.G. Vingerling, J.R. Klaver, C.C.W. Duijn, C.M. van Ikram, M.K. Jansonius, N.M. Jong, P.T.V.M. de Bergen, A.A.B Isaacs, A.J. Amin, N. Aulchenko, Y.S. Wolfs, R.C.W. |
2010-06-01
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Genome-wide linkage analysis of serum creatinine in three isolated European populations
(Article)
Pattaro, C. Aulchenko, Y.S. Hastie, N. Lauc, G. Meitinger, T. Oostra, B.A. Gyllensten, U. Wilson, J.F. Pichler, I. Hicks, A.A. Campbell, H. Wright, A.F. Isaacs, A.J. Rudan, I. Duijn, C.M. van Riegler, P. Marroni, F. Pramstaller, P.P. Vitart, V. Hayward, C. Franklin, C.S. Polasek, O. Kolcic, I. Biloglav, Z. Campbell, S. |
2009-08-01
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Familial aggregation of preeclampsia and intrauterine growth restriction in a genetically isolated population in The Netherlands
(Article)
Berends, A.L. Steegers, E.A.P. Isaacs, A.J. Aulchenko, Y.S. Liu, F. Groot, C.J.M. de Oostra, B.A. Duijn, C.M. van |
2008-07-10
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The apolipoprotein E gene and its age-specific effects on cognitive function
(Article)
Liu, F. Pardo Cortes, L.M. Janssens, A.C.J.W. Swieten, J.C. van Aulchenko, Y.S. Oostra, B.A. Duijn, C.M. van Schuur, M. Sanchez-Juan, P. Isaacs, A.J. Sleegers, K. Koning, I. de Zorkoltseva, I.V. Axenovich, T.I. Witteman, J.C.M. |
2008-01-01
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Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology
(Article)
Rijn, M.J.E. van Bos, M.J. Hofman, A. Breteler, M.M.B. Duijn, C.M. van Isaacs, A.J. Yazdanpanah, M. Arias-Vásquez, A. Stricker, B.H.Ch. Oostra, B.A. Klungel, O.H. Koudstaal, P.J. Witteman, J.C.M. |
2007-10-01
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Genetic Epidemiology and Lipids: A Pattern So Grand and Complex
(Doctoral Thesis)
Isaacs, A.J. |
2007-05-16
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Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk
(Article)
Rijn, M.J.E. van Bos, M.J. Yazdanpanah, M. Isaacs, A.J. Arias-Vásquez, A. Koudstaal, P.J. Hofman, A. Witteman, J.C.M. Duijn, C.M. van Breteler, M.M.B. |
2006-12-01
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