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muc 2ϫ/ϫ mice expression colon muc 2/il mice level muc 2 promoter rotaviru infection wt mice butyrate rotavirus infection protein effect caco -2 cells virus promoter coliti pge 2 foxa 1 factor figure inhibitor mucin muc 2 expression indomethacin goblet cells foxa 2 goblet concentration epithelial activity muc 2à/à mice ls 174t cells study signi inhibition synthesis muc 2 signi ficantly increase number result histone replication 5 weeks response transcription cytokine presence analysis development ficantly crypt il -10à/à mice prostaglandin disease binding cox activity addition cox inhibitors culture culture medium pathway physiol p 28. flammatory gene expression levels 37° c speci netherland activation 28. differentiation mucus layer cancer proliferation tff 3 experiment mouse -10à/à
6 Most Recent Publications
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Colitis development during the suckling-weaning transition in mucin muc2-deficient mice
(Article)
Paassen, N.B.-V. Sluis, M. van der Bouma, J. Korteland-Van Male, A.M. Lu, P. Seuningen, I. van Boehm, G. Goudoever, J.B. van Renes, I.B. |
2011-10-01
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The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: Implications for epithelial protection
(Article)
Burger-van Paassen, N. Vincent, A. Puiman, P.J. Sluis, M. van der Bouma, J. Boehm, G. Goudoever, J.B. van Seuningen, I. van Renes, I.B. |
2009-06-01
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Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: Mucin 2-interleukin 10-deficient mice
(Article)
Sluis, M. van der Bouma, J. Vincent, A. Velcich, A. Carraway, K.L. Büller, H.A. Einerhand, A.W.C. Goudoever, J.B. van Seuningen, I. van Renes, I.B. |
2008-06-24
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Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells
(Article)
Sluis, M. van der Vincent, A. Bouma, J. Male, A.K.V. Goudoever, J.B. van Renes, I.B. Seuningen, I. van |
2008-05-16
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Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection
(Article)
Raaben, M. Einerhand, A.W.C. Taminiau, L.J.A. Houdt, M. van Bouma, J. Raatgeep, R.H. Büller, H.A. Haan, C.A.M. de Rossen, J.W. |
2007-06-25
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Inhibition of cyclooxygenase activity reduces rotavirus infection at a postbinding step.
(Article)
Rossen, J.W. Bouma, J. Raatgeep, R.H. Büller, H.A. Einerhand, A.W.C. |
2004-09-01
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