Waard, H. de

repair damage es cells -/- −/− sensitivity lesion oxidative mutation protein dna damage response syndrome genome oxidative dna damage apoptosi polymerase cockayne mouse rna polymerase ii defect excision nucleotide excision repair transcription tc-ner dna repair ficient van der horst cancer hoeijmaker nucleotide strand cycle difference function cell types pathway survival group mechanism cockayne syndrome effect xeroderma exposure van steeg csb -/- pigmentosum figure csa -/- mefs gg-ner animal study cause tumor patient treatment xpa −/− transcription-coupled repair experiment mrad 175 oxidative damage csb -/- mefs hypersensitivity synthesis chapter factor keratinocyte van zeeland mrad 17 fibroblast uv sensitivity contrast cell lines csb −/− radiation paraquat wild-type xpa -/- liver csb −/− mice