Andressoo, J.O.

repair xpdttd xpbxpc oxidative damage sensitivity allele −/− syndrome mouse animal lesion oxidative dna damage transcription defect mutation cockayne protein tfiih experiment rna polymerase ii / xpc phenotype van der horst patient feature survival xeroderma pigmentosum polymerase level function ficient model csb −/− mefs cockayne syndrome compound hoeijmaker difference cell lines xeroderma pigmentosum oxidative dna lesions xpa xpbxpcs mice csb −/− response effect error bars xpbxpcs mice cause life span wild-type transcription-coupled repair progeroid nucleotide excision repair group gamma-ray xpa −/− paraquat result interallelic complementation figure genotype csa ϫ/ϫ mefs analysis oxidative damage cancer es cells phenotypic mouse models erasmus mc gamma-ray sensitivity table assay mutant basal complementation csb −/− mice growth csb-de ficient cells xpbxpcs xpdttd mice