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ghrelin administration insulin level insulin sensitivity ag ϩ uag subject effect glucose kojima m serum gh-deficient subjects endocrinol metab hosoda h placebo concentration study sensitivity change kangawa k lunch secretion replacement dose growth serum glucose levels combination hormone injection kangawa acylated kojima acylated ghrelin gh-deficient october peptide hosoda • effects receptor increase replacement baseline endocrinology study drug nakazato m ffa levels unacylated ghrelin ghrelin levels 2– 6 h serum insulin levels human fasting assay gauna insulin resistance insulin secretion papotti m secretagogue novel stomach table unacylated percent mondal ms metabolism ghigo gh action downloaded growth hormone iv administration plasma expression parameter figure nakazato papotti action pancreatic pancreatic - cells ϯ sem
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Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.
(Article)
Gauna, C. Meyler, F.M. Janssen, J.A.M.J.L. Delhanty, P.J.D. Abribat, T. Koetsveld, P.M. van Hofland, L.J. Broglio, F. Ghigo, E. Lely, A.J. van der |
2004-10-01
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