Van, N.M.

mutation n /c interaction receptor q 902k mutation interaction androgen activation ar q 902k domain androgen receptor binding ligand cho cells wild-type ar residue transcription protein activity wild-type assay endocrinol presence analysis concentration transcription activation hormone structure coactivator /well ar.n 1 tif 2 androgen insensitivity syndrome expression study patient metab insensitivity dissociation transactivation brinkmann phosphorylation transcriptional result ligand binding domain residue q 902 dose-response curve ar transcription activation function q 902 residue effect wilson october amount brinkmann ao luc assay curve transcriptional activity ar.c-q ar.c-q 902k kemppainen ja dose-response absence phenotype syndrome van der korput tif 2 activation transfected 1881. downloaded trapman january tif 2 transactivation trapman j dose-response curves androgen insensitivity kd value r 1881 acid residues ruiter pe ligand-binding domain