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expression number sample probe patient study infant leukemia gene expression mirna model microarray analysis figure subtype mll-rearranged platform power group table genomic lymphoblastic leukemia methylation level array chromosome region value copy number cancer effect mll-rearranged infant filter result method probe sets fication lymphoblastic cohort change blood association ratio precursor b-all expression levels genome population children microarray platforms translocation signature feature protein citation purposes page number bone marrow samples cluster statistic pattern .001 signi distribution netherland approach gene-set model exposure fusion difference myeloid leukemia ampli outcome precursor b-all research island erasmus mc gene sets dna methylation microrna cytogenetic
10 Most Recent Publications
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MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia
(Article)
Schotte, D. Menezes, R.X. de Moqadam, F.A. Khankahdani, L.M. Lange-Turenhout, E.A.M. Chen, C. Pieters, R. Boer, M.L. den |
2011-05-01
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Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia
(Article)
Balgobind, B.V. Heuvel-Eibrink, M.M. van den Cayuela, J.M. Baruchel, A. Meyer, C. Marschalek, R. Trka, J. Stary, J. Beverloo, H.B. Pieters, R. Zwaan, C.M. Boer, M.L. den Menezes, R.X. de Reinhardt, D. Hollink, I.H.I.M. Arentsen-Peters, S.T.C.J.M. Wering, E.R. van Kaspers, G.J. Cloos, J. Bont, E.S.J.M. de |
2011-02-01
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Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale
(Article)
Stumpel, D.J.P.M. Schotte, D. Lange-Turenhout, E.A.M. Schneider, P. Seslija, L. Menezes, R.X. de Marquez, V.E. Pieters, R. Boer, M.L. den Stam, R.W. |
2010-11-30
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Filtering, FDR and power
(Article)
Iterson, M. van Boer, J.M. Menezes, R.X. de |
2010-09-07
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Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants
(Article)
Stam, R.W. Schneider, P. Hagelstein, J. Linden, M.H. van der Stumpel, D.J.P.M. Menezes, R.X. de Lorenzo, P. de Valsecchi, M.G. Pieters, R. |
2010-04-08
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Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
(Article)
Stumpel, D.J.P.M. Schneider, P. Roon, E.H.J. van Boer, J.M. Lorenzo, P. de Valsecchi, M.G. Menezes, R.X. de Pieters, R. Stam, R.W. |
2009-12-24
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Relative power and sample size analysis on gene expression profiling data
(Article)
Iterson, M. van Hoen, P.A.C. 't Pedotti, P. Hooiveld, G.J.E.J. Dunnen, J.T. den Ommen, G.J.B. van Boer, J.M. Menezes, R.X. de |
2009-09-17
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Integrated analysis of DNA copy number and gene expression microarray data using gene sets
(Article)
Menezes, R.X. de Boetzer, M. Sieswerda, M. Ommen, G.J.B. van Boer, J.M. |
2009-06-29
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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
(Article)
Boer, M.L. den Slegtenhorst, M. van Horstmann, M.A. Janka-Schaub, G.E. Kamps, W.A. Evans, W.E. Pieters, R. Menezes, R.X. de Cheok, M.H. Buijs-Gladdines, J.G.C.A.M. Peters, S.T. Zutven, L.J.C.M. van Beverloo, H.B. Spek, P.J. van der Escherich, G. |
2009-02-01
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Can subtle changes in gene expression be consistently detected with different microarray platforms?
(Article)
Pedotti, P. Hoen, P.A.C. 't Boer, J.M. Menezes, R.X. de Vreugdenhil, E. Schenk, G.J. Vossen, R. Ariyurek, Y. Hollander, M. de Kuiper, R. Ommen, G.J. van Dunnen, J.T. den |
2008-03-10
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