View Author
osteoblast differentiation culture protein mineralization osteoblast differentiation activity expression matrix level effect 11- stretch control sv-hfo study nondifferentiating 1/2 glucocorticoid treatment loading b-catenin presence factor experiment increase erk 1/2 phosphorylation period pathway calcium strain extracellular condition actin formation osteoblastic regulation research b-catenin levels promoter phosphorylation signi collagen 15 min alp activity process stage result peptide kinase osteogenic difference medium analysis hsd 11b promoter activation osteogenic factors proteome research vol 11- hsd 1 inhibitor journal pre-mineralization period phosphatase activity absence nondifferentiating osteoblasts sv-hfo cells van leeuwen jp response function day 14 eijken pre-mineralization alpl activity dex treatment mmp -3 mechanism proteomic cytoplasmic tissue cyclic stretch
9 Most Recent Publications
|
Proteomic Analysis of Human Osteoblastic Cells: Relevant Proteins and Functional Categories for Differentiation
(Article)
Alves, R.D.A.M. Eijken, H.J.M. Swagemakers, S.M.A. Chiba, H. Titulaer, M.K. Burgers, P.C. Luider, T.M. Leeuwen, J.P.T.M. van |
2010-09-01
|
|
1α,25-(OH)2D3 acts in the early phase of osteoblast differentiation to enhance mineralization via accelerated production of mature matrix vesicles
(Article)
Woeckel, V.J. Alves, R.D.A.M. Swagemakers, S.M.A. Eijken, H.J.M. Chiba, H. Eerden, B.C.J. van der Leeuwen, J.P.T.M. van |
2010-05-19
|
|
1α,25-(OH)2D3 acts in the early phase of osteoblast differentiation to enhance mineralization via accelerated production of mature matrix vesicles
(Article)
Woeckel, V.J. Alves, R.D.A.M. Swagemakers, S.M.A. Eijken, H.J.M. Chiba, H. Eerden, B.C.J. van der Leeuwen, J.P.T.M. van |
2010-05-01
|
|
A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone
(Article)
Bruedigam, C. Eijken, H.J.M. Koedam, M. Peppel, J. van de Drabek, K. Chiba, H. Leeuwen, J.P.T.M. van |
2010-03-08
|
|
Stretch-Induced Inhibition of Wnt/b-Catenin Signaling in Mineralizing Osteoblasts
(Article)
Jansen, J.H.W. Eijken, H.J.M. Jahr, H. Chiba, H. Verhaar, J.A.N. Leeuwen, J.P.T.M. van Weinans, H.H. |
2010-03-01
|
|
Wnt signaling acts and is regulated in a human osteoblast differentiation dependent manner
(Article)
Eijken, H.J.M. Meijer, I.M.J. Westbroek, I. Koedam, M. Chiba, H. Uitterlinden, A.G. Pols, H.A.P. Leeuwen, J.P.T.M. van |
2008-05-15
|
|
Stretch-induced modulation of matrix metalloproteinases in mineralizing osteoblasts via extracellular signal-regulated kinase-1/2
(Article)
Jansen, J.H.W. Jahr, H. Verhaar, J.A.N. Pols, H.A.P. Chiba, H. Weinans, H.H. Leeuwen, J.P.T.M. van |
2006-07-01
|
|
11beta-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation.
(Article)
Hewison, M. Cooper, M.S. Jong, F.H. de Chiba, H. Stewart, P.M. Uitterlinden, A.G. Pols, H.A.P. Leeuwen, J.P.T.M. van Eijken, H.J.M. |
2005-03-01
|
|
Stretch-induced phosphorylation of ERK1/2 depends on differentiation stage of osteoblasts
(Article)
Jansen, J.H.W. Weyts, F.A.A. Westbroek, I. Jahr, H. Chiba, H. Pols, H.A.P. Verhaar, J.A.N. Leeuwen, J.P.T.M. van Weinans, H.H. |
2004-10-01
|
