Stewart, P.M.

glucocorticoid activity cushing 11␤- expression osteoblast treatment disease patient endocrinol syndrome culture differentiation effect cortisol osteoblast differentiation synovial fi broblasts level surgery therapy tumor il -1β dehydrogenase metab promoter induction dexamethasone hsd 11b promoter study flammatory 11␤- hsd 1 clin endocrinol sv-hfo broblast transsphenoidal surgery cytokine control cortisone result 11β- hsd 1 transsphenoidal hydroxysteroid synovial nondifferentiating proin flammatory cytokines production alp activity mineralization protein receptor ectopic adrenalectomy dex treatment grossman ab adipocyte corticotroph response ϯ sem radiotherapy endocrinology nondifferentiating osteoblasts value regulation region flammatory cytokines c /ebp remission increase secretion medium factor mg -63 cells downloaded sv-hfo cells arthritis tissue presence management consensus nelson