Yamamoto, M.

gata 1 erythroid protein expression factor transcription differentiation ad 5δe level blood figure lcr-g erythropoiesi hematopoietic transgene vector protein ix result transduction development ko-tx erythroid cells orkin progenitors erythroid differentiation number mouse control mutation analysis virus promoter binding rescue gata 2 regulation adenoviru ko-tx mice adult spleen domain region orkin sh interaction transcription factors lineage activation megakaryocyte activity ko-mx 1-null gata 1-null mutation liver treatment finitive erythropoiesis study speci hrd-g -finger signi ficantly capsid expression levels transcription factor gata embo j n -finger tx treatment stage finitive function globin signi phenotype gata 1. wt mice gata 1 function terminal adenovirus 5 vectors antibody maturation erythroblast