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scopus: 7101741871

Danhof, M.

(Meindert Danhof)


model concentration population patient morphine pharmacokinetic children neonate clearance study parameter covariate dataset value propofol distribution dosing analysis estimate blood infant variability infusion volume sample paediatric allometric bodyweight postnatal age effect umbilical serum parameter estimates amoxicillin method error allometric model pharmacol function result preterm prediction range labour information netherland covariate model regimen pharmacokinet validation table postnatal postmenstrual age weight evaluation metabolite interindividual variability group clindamycin venous umbilical cord figure antibiotic body weight simulation venou women 10 days adult change elimination pharmacokinetic model umbilical cord level influence number knibbe agents chemother penicillin g dosing regimen penicillin




10 Most Recent Publications

Maturation of the glomerular filtration rate in neonates, as reflected by amikacin clearance (Article)
Cock, R.F.W. De Allegaert, K. Schreuder, M.F. Sherwin, C.M.T. Hoog, M. de Anker, J.N. van den Danhof, M. Knibbe, C.A.
2012-01-23
The role of population PK-PD modelling in paediatric clinical research (Article)
Cock, R.F.W. De Piana, C. Krekels, E.H.J. Danhof, M. Allegaert, K. Knibbe, C.A.
2011-05-01
Systematic evaluation of the descriptive and predictive performance of Paediatric morphine population models (Article)
Krekels, E.H.J. Hasselt, J.G.C. van Tibboel, D. Danhof, M. Knibbe, C.A.
2011-04-01
Predictive performance of a recently developed population pharmacokinetic model for morphine and its metabolites in new datasets of (preterm) neonates, infants and children (Article)
Krekels, E.H.J. DeJongh, J. Lingen, R.A. van Marel, C.D. van der Choonara, I. Lynn, A.M. Danhof, M. Tibboel, D. Knibbe, C.A.
2011-01-01
Pharmacokinetics of clindamycin in pregnant women in the peripartum period (Article)
Muller, A.F. Mouton, J.W. Oostvogel, P.M. Dörr, P.J. Voskuyl, R.A. DeJongh, J. Steegers-Theunissen, R.P.M. Danhof, M.
2010-05-01
Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model (Article)
Peeters, M.Y. Allegaert, K. Bluss van Oud-Alblas, H.J. Cella, M. Tibboel, D. Danhof, M. Knibbe, C.A.
2010-03-19
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years (Article)
Knibbe, C.A. Krekels, E.H.J. Tibboel, D. Anker, J.N. van den DeJongh, J. Santen, G.W.E. Dijk, M. van Simons, S.H.P. Lingen, R.A. van Jacqz-Aigrain, E.M. Danhof, M.
2009-08-12
Pharmacokinetics of amoxicillin in maternal, umbilical cord, and neonatal sera (Article)
Muller, A.F. Oostvogel, P.M. DeJongh, J. Mouton, J.W. Steegers, E.A.P. Joep Dörr, P. Danhof, M. Voskuyl, R.A.
2009-04-01
Tailor-made drug treatment for children. Creation of an infrastructure for data-sharing and population PK-PD modeling (Article)
Ince, I. Wildt, S.N. de Tibboel, D. Danhof, M. Knibbe, C.A.
2009-03-01
The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women (Article)
Muller, A.F. Dörr, P.J. Mouton, J.W. Jongh, J. de Oostvogel, P.M. Steegers, E.A.P. Voskuyl, R.A. Danhof, M.
2008-12-01