Chaplin, P.J.

animal vaccination group virus vaccine smallpox challenge vaccinated smallpox vaccines antibody mva-bn plasma vaccinia control animals 107 pfu elstree-rivm infection temperature response titer assay throat swabs ef ficacy monkeypox study strain control 37° c 106 pfu group ϯ sd elstree-bn throat sample neutralizing speci signi fi nal concentration fi rst vaccination neutralizing antibody titers vero cell monolayers difference macaque plaque peak levels germany poxvirus particles netherland reduction macaca fascicularis mpxv challenge neutralizing antibodies ficacy monkeypox virus group iii group i monkey plate isolation poxviru fi broblasts room temperature day 28. cynomolgu puri fied mva lesion vaccinia virus strain vaccinated animals log 10 values stittelaar attenuated alveolar wall monkeypox virus infection plaque reduction assay variola virus collagen fi bers vaccination regimens alveolar virus isolation plasma dilutions broblast