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scopus: 6602978779

Stearne, L.E.T.

(Lorna Stearne)


trova floxacin abscess floxacin fragili trova strain treatment culture cloacae effect concentration activity agents chemother infection antibiotic study chemother antimicrob mutant agent model count ef ficacy resistance number fragilis atcc 23745 moxi floxacin inoculation ficacy ratio liposomes regimen signi ambisome netherland cloacae 22491 weight dosing ec 50 therapy group rmg-csf dosing regimens inocula amb-lip result reduction difference blood peg-amb-lip emergence trova floxacin concentrations antimicrobial bacteroides fragilis stearne czx-resistant selection combination coli atcc 25922 enterobacter animal control rmg-csf prophylaxis inoculum abscess weights 5 days table plate pharmacokinetic frequency ficant cephalosporin albicans moxi floxacin treatment czx-resistant e prophylaxi increase cloacae mutants 108 cfu /ml bacteria




6 Most Recent Publications

Effect of dosing and dosing frequency on the efficacy of ceftizoxime and the emergence of ceftizoxime resistance during the early development of murine abscesses caused by Bacteroides fragilis and Enterobacter cloacae mixed infection (Article)
Stearne, L.E.T. Goessens, W.H.F. Mouton, J.W. Gyssens, I.C.J.
2007-10-01
Effect of recombinant murine granulocyte colony-stimulating factor with or without fluoroquinolone therapy on mixed-infection abscesses in mice. (Article)
Stearne, L.E.T. Vonk, A.G. Kullberg, B.J. Gyssens, I.C.J.
2005-09-01
Comparative study of the effects of ceftizoxime, piperacillin, and piperacillin-tazobactam concentrations on antibacterial activity and selection of antibiotic-resistant mutants of Enterobacter cloacae and Bacteroides fragilis in vitro and in vivo in mixed-infection abscesses (Article)
Stearne, L.E.T. Boxtel, D. van Lemmens, N. Goessens, W.H.F. Mouton, J.W. Gyssens, I.C.J.
2004-01-01
In vivo efficacy of trovafloxacin against Bacteroides fragilis in mixed infection with either Escherichia coli or a vancomycin-resistant strain of Enterococcus faecium in an established-abscess murine model. (Article)
Stearne, L.E.T. Gyssens, I.C.J. Goessens, W.H.F. Mouton, J.W. Oyen, W.J. Meer, J.W. van der Verbrugh, H.A.
2001-05-07
In vitro activity of trovafloxacin against Bacteroides fragilis in mixed culture with either Escherichia coli or a vancomycin- resistant strain of Enterococcus faecium determined by an anaerobic time-kill technique. (Article)
Stearne, L.E.T. Kooi, C. Goessens, W.H.F. Bakker-Woudenberg, I.A.J.M. Gyssens, I.C.J.
2001-01-16
Amphotericin B liposomes with prolonged circulation in blood: in vitro antifungal activity, toxicity, and efficacy in systemic candidiasis in leukopenic mice (Article)
Etten, E.W.M. van Kate, M.T. ten Stearne, L.E.T. Bakker-Woudenberg, I.A.J.M.
1995-01-01