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-170 dynein clip -170 bicd 2 spindle protein figure centrosome ranbp sirna microtubule gfp-clip mutation 18ink bipolar antibody nucleus hela cells control function manchette gfp-clip -170 result depletion transfected kinesin mitotic 2os cells motor dynactin ranbp 2 p 18ink testi spermatid analysis clip -170 ko expression spindle bipolarity bipolar spindles tumor separation clip -115 g 2 phase kif 5b prophase interaction experiment activity staining domain -115 localization lis 1 10 mm nocodazole bipolar spindle assembly study region biology image transfection cdk 4 bipolar spindle p 150glued eg 5 activity percentage cancer mitotic cells development fragment tubulin cytoplasmic p 18ink proteins hela cells stably binding centrosome separation 3 min interval nuclei level bipolarity dhc-depleted cells
4 Most Recent Publications
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Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry
(Article)
Splinter, D. Tanenbaum, M.E. Demmers, J.A. Fornerod, M.W.J. Melchior, F. Hoogenraad, C.C. Medema, R.H. Akhmanova, A. Lindqvist, A. Jaarsma, D. Flotho, A. Yu, K.L. Grigoriev, I. Engelsma, D. Haasdijk, E.D. Keijzer, N. |
2010-04-01
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P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development
(Article)
Veelen, W. van Klompmaker, R. Gloerich, M. Gasteren, C.J.R. van Kalkhoven, E. Berger, R. Lips, C.J.M. Medema, R.H. Höppener, J.W.M. Acton, D.S. |
2009-01-15
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Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly
(Article)
Tanenbaum, M.E. Macůrek, L. Galjart, N.J. Medema, R.H. |
2008-12-17
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The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis.
(Article)
Akhmanova, A. Mausset-Bonnefont, A.L. Meulen, H. van der Tanenbaum, M.E. Medema, R.H. Hoogerbrugge, J.W. Vreeburg, J.T.M. Uringa, E.J. Grootegoed, J.A. Grosveld, F.G. Galjart, N.J. Cappellen, W.A. van Keijzer, N. Hoogenraad, C.C. Stepanova, T. Drabek, K. Wees, J. van der Mommaas, M. Onderwater, J. |
2005-10-15
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