Herzenberg, L.A.

thymocyte ␤- catenin expression subset catenin level thymocyte subsets t cell development stage development dn 1 stage thymu mouse pnas web site murine thymic result immunol block clever intracellular receptor thymocyte development population dephosphorylated ␤- catenin protein component erasmus mc vector weerkamp dn cells study experiment signal differentiation rq-pcr molecule adenomatous polyposis coli transduction pathway information wnt pathway control tcf-dependent gfp expression cd 34ϩcd cells stanford university school blood thymic organ culture cord blood wnt signals staal 103 ͉ factor intracellular wnt tcf binding sites ␤- catenin levels 34ϩcd transcription target transduced function lentiviral nature reporter thymocyte differentiation thymic subsets t cells antibody overexpression isp stages plakoglobin thymic stroma murine thymus cd 8ϩcd expression levels plasmid jurkat cells tcf-dependent binding control vector