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effect ifn -β growth treatment receptor type i ifns ghrelin expression cancer ifnar control interferon unacylated ghrelin ifn - igf-ii ifn -␣ apoptosi activity protein tumor sw -13 cells pancreatic unacylated concentration bxpc -3 cells 3 days inhibition combination signi cycle h 295 cells factor medium activation dna fragmentation incubation ifn -β1a ifnar -2c adrenocortical igf-i ifn -α type i interferons response proliferation pancreatic cancer van koetsveld pm signi ficantly level acylated carcinoma hormone vitale study -13 bxpc -3 secretion antitumor activity pathway increase sw 13 cells culture metab analysis experiment fragmentation miapaca caspase p 27 expression phosphorylation phase *** igf-ir endocrinol ifn -α2b cell cycle arrest cytokine ficantly antitumor assay 6 days
6 Most Recent Publications
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The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells
(Article)
Vitale, G. Zappavigna, S. Piccoletti, R. Koetsveld, P.M. van Cavagnini, F. Budillon, A.M. Abbruzzese, A. Hofland, L.J. Caraglia, M. Marra, M. Dicitore, A. Meschini, S. Condello, M. Arancia, G. Castiglioni, S. Maroni, P. Bendinelli, P. |
2012-01-01
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Potential role of type i interferons in the treatment of pituitary adenomas
(Article)
Vitale, G. Caraglia, M. Koetsveld, P.M. van Maroni, P. Marra, M. Colao, A. Lamberts, S.W.J. Cavagnini, F. Hofland, L.J. |
2009-06-01
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Effects of type I interferons on IGF-mediated autocrine/paracrine growth of human neuroendocrine tumor cells
(Article)
Vitale, G. Koetsveld, P.M. van Herder, W.W. de Wansem, K. van der Janssen, J.A.M.J.L. Colao, A. Lombardi, G. Lamberts, S.W.J. Hofland, L.J. |
2009-03-01
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Type I interferons in the treatment of pancreatic cancer: Mechanisms of action and role of related Receptors
(Article)
Vitale, G. Eijck, C.H.J. van Lamberts, S.W.J. Hofland, L.J. Koetsveld Ing, P.M. van Erdmann, J. Speel, E.J. Wansem Ing, K. van der Mooij, D.M. Colao, A. Lombardi, G. Croze, E. |
2007-08-01
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Ghrelin and its unacylated isoform stimulate the growth of adrenocortical tumor cells via an anti-apoptotic pathway
(Article)
Delhanty, P.J.D. Koetsveld, P.M. van Gauna, C. Zande, B. van de Vitale, G. Hofland, L.J. Lely, A.J. van der |
2007-07-01
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Potent inhibitory effects of type I interferons on human adrenocortical carcinoma cell growth.
(Article)
Koetsveld, P.M. van Vitale, G. Lamberts, S.W.J. Hofland, L.J. Herder, W.W. de Feelders, R.A. Wansem, K. van der Waaijers, M. Eijck, C.H.J. van Speel, E.J. Croze, E. Lely, A.J. van der |
2006-11-01
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