Oostvogel, P.M.

concentration patient model study strain umbilical amoxicillin blood women pharmacokinetic group labour serum population clindamycin sample netherland venous umbilical cord antibiotic analysis parameter disease venou distribution umbilical cord value colonizing serotype marker interindividual variability estimate blood samples streptococcu 0.094 volume neonate group b streptococcus group b streptococci infusion taiwanese variability resistance protein binding difference pregnancy agents chemother nonmem fi nal model delivery 0.047 mother error table liter covariate virulence interindividual 0.064 protein binding compartment dutch interval prevalence microbiol result ratio goodness-of -fit plots administration effect agalactiae onset postpartum period streptococcus agalactiae gbs disease dosing muller department ef ficacy level