Berkel, Th.J.C. van

pyruvate kinase enzyme activity concentration liver pyruvate kinase l-type pyruvate kinase alanine presence l-type value fru-r biophy patient m-type erythrocyte pyruvate kinase pyruvate kinase activity leucocyte rat liver inhibition biochem effect 0.5 expression group property absence p-enolpyruvate affinity van berkel erythrocyte allosteric biochim koster m-type pyruvate kinase mercaptoethanol curve berkel result parenchymal cells glutathione influence incubation phosphoenolpyruvate protein parenchymal tanaka condition phosphorylated hexoses control study non-parenchymal cells leucocyte cetp expression tissue table hexose pyruvate kinase-deficient patients cholesterol uap patients level method thiol groups alanine inhibition cetp tg mice phosphorylated mgatp paper reaction regulation difference 0.1 increase kinetic non-parenchymal netherland addition 1 mm alanine blood transfer