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scopus: 20735691500

Zande, B. van de

(Bedette van de Zande)


ghrelin insulin effect receptor unacylated ghrelin glucose growth response unacylated ivgtt concentration level ghs-r portal sw -13 cells obestatin acylated hormone treatment control administration peptide metab study signi endocrinol library erasmus mc secretagogue -13 circulation adrenocortical expression portal vein experiment insulin secretion group oleic ghs-r 1a secretion membrane signi ficantly activity medium fi ndings antagonist insulin levels function saline acylated ghrelin insulin sensitivity lipid endocrinology 2004. assay gauna sensitivity ec 50 downloaded cholesterol ghigo e system 30 nmol /kg ghs-r 1a antagonist insulin concentrations baseline food intake mechanism curve ghsr /aequorin cells oleic acid treatment administration kangawa k internalization erasmu release ficant pathway condition animal nding




5 Most Recent Publications

Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization (Article)
Delhanty, P.J.D. Kerkwijk, A. Huisman, M. Zande, B. van de Verhoef-Post, M. Gauna, C. Hofland, L.J. Themmen, A.P.N. Lely, A.J. van der
2010-09-01
Bolus administration of obestatin does not change glucose and insulin levels neither in the systemic nor in the portal circulation of the rat (Article)
Kiewiet-Kemper, R.M. Gauna, C. Aken, M.O. van Zande, B. van de Lely, A.J. van der
2008-12-01
Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions (Article)
Gauna, C. Kiewiet-Kemper, R.M. Janssen, J.A.M.J.L. Zande, B. van de Delhanty, P.J.D. Ghigo, E. Hofland, L.J. Themmen, A.P.N. Lely, A.J. van der
2007-09-01
Unacylated ghrelin is not a functional antagonist but a full agonist of the type 1a growth hormone secretagogue receptor (GHS-R) (Article)
Gauna, C. Zande, B. van de Kerkwijk, A. Themmen, A.P.N. Lely, A.J. van der Delhanty, P.J.D.
2007-08-15
Ghrelin and its unacylated isoform stimulate the growth of adrenocortical tumor cells via an anti-apoptotic pathway (Article)
Delhanty, P.J.D. Koetsveld, P.M. van Gauna, C. Zande, B. van de Vitale, G. Hofland, L.J. Lely, A.J. van der
2007-07-01