Sanchez-Juan, P.

disease patient protein study creutzfeldt-jakob disease analysis creutzfeldt-jakob diagnosis region genotype allele mutation tremor 14-3-3 control neurol result table neurology association level cerebrospinal fl uid brain marker signi onset group prion sensitivity alzheimer disease duration university duration linkage creutzfeldt –jakob disease chromosome stage fi ndings subtype scjd cases disorder ficant number sample family effect nding haplotype department codon polymorphism parkin position movement criteria signi ficant function sanchez-juan prion protein gene value genetic difference apoe *e tau protein zerr i population genet cerebrospinal 14-3-3 test carrier surveillance codon 129 genotype speci ficity signi ficantly flair evidence distribution prnp g 310c erasmus university rotterdam health