White, A.

glucocorticoid patient receptor expression tumor effect variant level glucocorticoid receptor hematological malignancies plasmid /well myeloma response sample 100 ng /well dexamethasone treatment cho cells transfection gr gene gc treatment gr-p expression hematological malignancy resistance study splice activity glucocorticoid receptor mrna transfection experiments pcdna 3.1 plasmid transfected tumor cells prostate carcinoma xenografts carcinoma pcdna netherland mm patients hela cells life technologies number mm cell lines tumor cell lines glucocorticoid receptor p university myeloma cell lines clai /xhoi fragment absence cotransfected mechanism rpmi 8226- control values presence leukemia sequence gc resistance cell lines signal gr message exon 9 primer primers marrow department concentration protein control isoform amount mutation experiment rotterdam factor gr-p splice variant prostate myeloid leukemia luc activity cmv promoter erasmus university rotterdam