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intake control study mother vitamin heart defect chd risk children nicotinamide level lipid vitamin e netherland vitamin e intake factor association heart defects periconception supplement homocysteine pregnancy disease chapter heart disease child women apolipoprotein period cholesterol group folic acid genotype medicine control mothers polymorphism family folic nicotinamide intake periconception period steegers-theunissen offspring dutch value centre parent 16 months folate analysis rotterdam apolipoprotein b result population b-vitamin phenotype table ratio steegers-theunissen rp european development erasmus mc expression case mothers month p-value allele tract effect risk factor energy 1.0 riboflavin haplotype erasmu oxidative stress profile frequency study moment chd phenotypes reference
7 Most Recent Publications
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Congenital Heart Disease: Vascular Risk Factors and Medication
(Doctoral Thesis)
Smedts, H.P.M. |
2011-02-02
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A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring
(Article)
Smedts, H.P.M. Uitert, E.M. van Valkenburg, O. Laven, J.S.E. Eijkemans, M.J.C. Lindemans, J. Steegers-Theunissen, R.P.M. |
2010-12-27
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VEGF polymorphisms are associated with endocardial cushion defects: A family-based case-control study
(Article)
Smedts, H.P.M. Isaacs, A. Costa, D. de Uitterlinden, A.G. Tikka-Kleemola, P. Gittenberger-De Groot, A.C. Helbing, W.A. Steegers-Theunissen, R.P.M. |
2010-01-01
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High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring
(Article)
Smedts, H.P.M. Vries, J.H. de Rakhshandehroo, M. Wildhagen, M.F. Verkleij-Hagoort , A.C. Steegers, E.A.P. Steegers-Theunissen, R.P.M. |
2009-02-01
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Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects
(Article)
Smedts, H.P.M. Rakhshandehroo, M. Verkleij-Hagoort , A.C. Vries, J.H. de Ottenkamp, J. Steegers, E.A.P. Steegers-Theunissen, R.P.M. |
2008-10-01
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Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide
(Article)
Driel, L.M.J.W. van Smedts, H.P.M. Helbing, W.A. Isaacs, A. Lindemans, J. Uitterlinden, A.G. Tikka-Kleemola, P. Vries, J.H. de Steegers-Theunissen, R.P.M. |
2008-06-01
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A more atherogenic serum lipoprotein profile is present in women with polycystic ovary syndrome: A case-control study
(Article)
Valkenburg, O. Steegers-Theunissen, R.P.M. Smedts, H.P.M. Dallinga-Thie, G.M. Fauser, B.C.J.M. Westerveld, E.H. Laven, J.S.E. |
2008-02-01
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