Bralten, L.B.C.

mutation glioma idh 1 tumor cancer expression sample caspr idh 1 mutations analysis non-p.r 132h mutations survival change glioblastoma caspr 2 caspr 2 gene region subtype number patient idh 2 mutations oligodendroglioma idh 1r grade isocitrate genomic identi fied protein study identi result array loss r 132h figure tumor suppressor gene level proliferation dehydrogenase fusion suppressor cell lines cluster caspr 2 expression brain frequency deletion activity non-p.r idh 1 mutation pathway odiii candidate table astrocytoma chapter glioma cell lines function bralten fication novel promoter alteration enzyme chromosome idh 1r cells histological proliferation rate van den 87 cells transcript idh 1wt treatment glioblastoma multiforme oncogene research tumour tumor suppressor genes translocation 2- hydroxyglutarate control