Jager, M. de

protein repair mre 11 hmre 11 activity ssdna binding damage recombination substrate dna substrates csa protein irradiation molecule dsdna double-strand dna ends annealing complex rad 50 fraction r /m oligomers reaction antibody dna molecules laser nijmegen breakage syndrome acids research presence pathway buffer experiment strand addition replication overhang dna damage hoechst oligonucleotide structure formation yeast 800 nm irradiation function concentration response hrad 52 matrix saccharomyces cerevisiae result nuclease incubation dna double-strand uv irradiation break figure petrini domain lesion 3- overhangs atpase method dna double-strand breaks rnap ii telomere natl acad hmre 11 protein research accumulation chromosome cerevisiae 15 min oligomer rad 54-gfp nucleotide excision repair mj 19 cell biol hoechst 33342 5- overhangs factor