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protein rad 51 figure recombination lament strand molecule binding activity rad 51ap formation clip -170 hmre 11 -170 reaction dsdna structure repair ssdna substrate length filament presence exchange disassembly interaction atp hydrolysis nucleation vesicle fl ow cell acids research rad 51 fi fen -1-xpg extension nucleoprotein p 150glued annealing single-stranded monomer strand exchange result experiment double-stranded dna single-stranded dna buffer function region monte carlo simulations oligonucleotide loop formation recombinase fi lament patch hydrolysis mre 11 -1-xpg dynactin 150glued condition concentration double-stranded assay terminus patch research fi lament extension dna molecules nucleotide rab 6 distance incubation spacer region dissociation assembly fi lament formation lis 1 control ammonium sulfate yeast study nuclease
10 Most Recent Publications
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Counting RAD51 proteins disassembling from nucleoprotein filaments under tension
(Article)
Mameren, J. van Modesti, M. Kanaar, R. Wyman, C. Peterman, E.J.G. Wuite, G.J.L. |
2009-02-05
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Homologous Recombination in Real Time: DNA Strand Exchange by RecA
(Article)
Heijden, T. van der Modesti, M. Hage, S. Kanaar, R. Wyman, C. Dekker, C. |
2008-05-23
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RAD51AP1 Is a Structure-Specific DNA Binding Protein that Stimulates Joint Molecule Formation during RAD51-Mediated Homologous Recombination
(Article)
Modesti, M. Budzowska, M. Baldeyron, C. Demmers, J.A. Ghirlando, R. Kanaar, R. |
2007-11-09
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Real-time assembly and disassembly of human RAD51 filaments on individual DNA molecules
(Article)
Heijden, T. van der Seidel, R. Modesti, M. Kanaar, R. Wyman, C. Dekker, C. |
2007-09-01
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Rab6 Regulates Transport and Targeting of Exocytotic Carriers
(Article)
Grigoriev, I. Splinter, D. Akhmanova, A. Keijzer, N. Wulf, P. Demmers, J.A. Ohtsuka, T. Modesti, M. Maly, I.V. Grosveld, F.G. Hoogenraad, C.C. |
2007-08-07
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Fluorescent Human RAD51 Reveals Multiple Nucleation Sites and Filament Segments Tightly Associated along a Single DNA Molecule
(Article)
Modesti, M. Ristic, D. Heijden, T. van der Dekker, C. Mameren, J. van Peterman, E.J.G. Wuite, G.J.L. Kanaar, R. Wyman, C. |
2007-05-16
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Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity
(Article)
Hohl, M. Dunand-Sauthier, I. Staresincic, L. Jaquier-Gubler, P. Thorel, F. Modesti, M. Clarkson, S.G. Schärer, O.D. |
2007-05-01
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Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function.
(Article)
Ristic, D. Modesti, M. Heijden, T. van der Noort, J. van Dekker, C. Kanaar, R. Wyman, C. |
2005-09-02
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Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization
(Article)
Lansbergen, G.W.A. Hoogenraad, C.C. Grosveld, F.G. Komarova, Y. Modesti, M. Wyman, C. Goodson, H.V. Lemaitre, R.P. Akhmanova, A. Drechsel, D.N. Munster, E. van Borisy, G.G. Gadella Jr, T.W. Galjart, N.J. |
2004-01-01
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DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways
(Article)
Jager, M. de Dronkert, M.L.G. Modesti, M. Beerens, C.E.M.T. Kanaar, R. Gent, D.C. van |
2001-01-01
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