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expression tumor cancer seminoma 12 p amplification testicular tcam -2 cells germ cells looijenga carcinoma sample analysis marker amplification germ cell tumors level chromosome differentiation protein tissue development tumours mutation result cell lines type ii gcts patient oosterhui tumour oosterhuis jw embryonal factor presence study embryonal carcinoma nanog testi figure lin 28 staining table tcfap mirna 3/4 pattern tcfap 2c tcam -2 region journal andrology number fication control c-kit nonseminoma oct 4b section cell line looijenga lhj apoptosi speci dad-r gilli oct 3/4 genomic probe pou 5f treatment germ cell tumours identi pathol chromosomal author identi fied origin pluripotency hybridization gillis aj methylation looijenga lh
10 Most Recent Publications
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The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression
(Article)
Nettersheim, D. Gillis, A.J. Biermann, K. Looijenga, L.H.J. Schorle, H. |
2011-12-01
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Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: Confirmation of OCT3/4 specificity for germ cell tumours
(Article)
Rijlaarsdam, M.A. Herk, H.A.D.M. van Looijenga, L.H.J. Gillis, A.J. Stoop, J.A. Jenster, G.W. Martens, J.W.M. Leenders, G.J. van Dinjens, W.N.M. Hoogland, A.M. Timmermans, A.M. |
2011-09-06
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Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance
(Article)
Looijenga, L.H.J. Gillis, A.J. Stoop, J.A. Biermann, K. Oosterhuis, J.W. |
2011-08-01
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TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cell line TCam-2 into a cell type resembling mixed non-seminoma
(Article)
Nettersheim, D. Gillis, A.J. Looijenga, L.H.J. Schorle, H. |
2011-08-01
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Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis
(Article)
Gillis, A.J. Stoop, J.A. Biermann, K. Gurp, R.J.H.L.M. van Swartzman, E. Cribbes, S. Ferlinz, A. Shannon, K.M. Oosterhuis, J.W. Looijenga, L.H.J. |
2011-08-01
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Diagnosis of testicular carcinoma in situ'(intratubular and microinvasive)' seminoma and embryonal carcinoma using direct enzymatic alkaline phosphatase reactivity on frozen histological sections
(Article)
Stoop, J.A. Kirkels, W.J. Dohle, G.R. Gillis, A.J. Bakker, M.A. den Biermann, K. Oosterhuis, J.W. Looijenga, L.H.J. |
2011-02-01
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Critical function of AP-2gamma/TCFAP2C in mouse embryonic germ cell maintenance
(Article)
Weber, S. Eckert, D. Schorle, H. Nettersheim, D. Gillis, A.J. Schäfer, S. Kuckenberg, P. Ehlermann, J. Werling, U. Biermann, K. Looijenga, L.H.J. |
2010-05-18
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Stem cell factor as a novel diagnostic marker for early malignant germ cells
(Article)
Stoop, J.A. Honecker, F.U. Dennis, N. Summersgill, B. Mclntyre, A. Shipley, M.J. Oosterhuis, J.W. Looijenga, L.H.J. Geijn, G.J.M. van de Gillis, A.J. Cools, M.B.C.M. Boer, M. de Bokemeyer, C. Wolffenbuttel, K.P. Drop, S.L.S. Krijger, R.R. de |
2008-09-01
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A Pure Triphasic Testicular Wilms Tumor of Primordial Germ Cell Origin
(Article)
Looijenga, L.H.J. Gillis, A.J. Oosterhuis, J.W. |
2008-07-01
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Further characterization of the first seminoma cell line TCam-2
(Article)
Jong, J. de Stoop, J.A. Baeten, J. Kitazawa, S. Zoelen, E.J.J. van Roozendaal, K.E. van Oosterhuis, J.W. Looijenga, L.H.J. Gillis, A.J. Hersmus, R. Gurp, R.J. van Geijn, G.J.M. van de Drunen, E. van Beverloo, H.B. Schneider, D.T. Sherlock, J.K. |
2008-03-01
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