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scopus: 6507149533

Valkhof, M.

(Marijke Valkhof)


expression myeloid leukemia receptor protein figure cebpa integration factor level virus csf 3r g-csf-r control differentiation analysis txnip blood yy 1 expression rtcgd myeloid leukemia g-csf result lineage -1.4 /eyfp transcription wt csf 3r hematopoietic c /ebp progenitor lysine fl ow cytometry mouse development kinase internalization progenitors primers cebpa /eyfp cells granulocyte colony-stimulating factor antibody granulocyte patient ba /f cells erkeland colony membrane eyfp ϩ lysine residues intron bone marrow cells lymphoid table marrow activation growth region colony-stimulating graffi intron 1 panel murine signi cell-surface binding number residue transcriptional cell-surface expression assay population eyfp ϩ cells study g-csf-rd wsb -2 virus integrations membrane expression signi ficantly domain




7 Most Recent Publications

Prevalence of a new auto-activating colony stimulating factor 3 receptor mutation (CSF3R-T595I) in acute myeloid leukemia and severe congenital neutropenia (Article)
Beekman, R. Valkhof, M. Strien, P. van Valk, P.J.M. Touw, I.P.
2013-05-01
Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors (Article)
Wölfler, A. Danen-van Oorschot, A.A. Haanstra, J.R. Valkhof, M. Bodner, C. Vroegindeweij, E.M. Strien, P. van Novak, A. Cupedo, T. Touw, I.P.
2010-11-18
The gene encoding thioredoxin-interacting protein (TXNIP) is a frequent virus integration site in virus-induced mouse leukemia and is overexpressed in a subset of AML patients (Article)
Erkeland, S.J. Palande, K.K. Valkhof, M. Gits, J. Oorschot, A.D.v. Touw, I.P.
2009-10-01
Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors. (Article)
Meenhuis, J.C.M. Irandoust, M. Wölfler, A. Roovers, O. Valkhof, M. Touw, I.P.
2009-02-01
Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation signaling (Article)
Erkeland, S.J. Aarts, L.H.J. Irandoust, M. Roovers, O. Klomp, A. Valkhof, M. Gits, J. Eyckerman, S. Tavernier, J. Touw, I.P.
2007-03-29
Large-scale identification of disease genes involved in acute myeloid leukemia (Article)
Erkeland, S.J. Valkhof, M. Heijmans-Antonissen, C. Hoven-Beijen, A. van Delwel, H.R. Hermans, M.H. Touw, I.P.
2004-01-01
The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation (Article)
Erkeland, S.J. Valkhof, M. Heijmans-Antonissen, C. Delwel, H.R. Valk, P.J.M. Hermans, M.H. Touw, I.P.
2003-01-01