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Hermans, M.H.

( M.H. Hermans)


receptor leukemia myeloid factor g-csf expression blood integration granulocyte virus differentiation activation protein tyrosine granulocyte colony-stimulating factor gcsfr yy 1 expression rtcgd colony-stimulating myeloid leukemia g-csf-r colony bone marrow cells -1.4 progenitor number mutation marrow patient level neutropenia figure stat 3 715 mice murine analysis kinase assay intron proliferation 715/ 715 mice growth transcription study graffi leukemic stat 3 activation intron 1 progenitor cells result signal region activity g-csfr hematopoietic g-csfinduced tumor pathway scn patients bm cells yy 1 gene tyr 764 tyr 729 mol cell biol transcriptional control neutrophil primers gcsfr gene cytokine mouse novel vector j biol chem table myeloid progenitor cells response netherland virus integrations medium




4 Most Recent Publications

Large-scale identification of disease genes involved in acute myeloid leukemia (Article)
Erkeland, S.J. Valkhof, M. Heijmans-Antonissen, C. Hoven-Beijen, A. van Delwel, H.R. Hermans, M.H. Touw, I.P.
2004-01-01
Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells (Article)
Hermans, M.H. Heijmans-Antonissen, C. Gits, J. Leeuwen, D. van Ward, A.C. Touw, I.P. Geijn, G.J.M. van de
2003-01-01
The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation (Article)
Erkeland, S.J. Valkhof, M. Heijmans-Antonissen, C. Delwel, H.R. Valk, P.J.M. Hermans, M.H. Touw, I.P.
2003-01-01
Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene (Article)
Hermans, M.H. Heijmans-Antonissen, C. Ward, A.C. Mayen, A.E. Ploemacher, R.E. Touw, I.P.
1999-01-01
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