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t cells patient transplantation function 25+ 25bright figure transplant expression induction effect blood level kidney control percentage study t-cell il -2 kidney transplant patients 25neg immunol foxp 3 therapy response cd 4+cd ratg-induced cd 25bright cells presence suppressive group tacrolimu proliferation granzyme b granzyme conversion number analysis suppression cd 25 chapter result inhibitor cd 25neg cells capacity bd biosciences assay inhibition tolerance cellen month cytokine antigen effector -10 cd 4+cd cells mechanism sample treatment cyclosporine rejection 25-/dim cd 25+ cd 25 expression stimulation activity target activation population antibody foxp 3 expression rabbit 24 hr donor pathway allogeneic memory receptor depletion factor
10 Most Recent Publications
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The Jak inhibitor CP-690,550 preserves the function of CD4 +CD25brightFoxP3+ regulatory T cells and inhibits effector T cells
(Article)
Sewgobind, V.D.K.D. Quaedackers, M.E. Laan, L.J.W. van der Kraaijeveld, R. Korevaar, S.S. Chan, G. Weimar, W. Baan, C.C. |
2010-08-01
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The calcineurin inhibitor tacrolimus allows the induction of functional CD4+CD25+ regulatory T cells by rabbit anti-thymocyte globulins
(Article)
Sewgobind, V.D.K.D. Laan, L.J.W. van der Kho, M.M.L. Kraaijeveld, R. Korevaar, S.S. Mol, W.M. |
2010-08-01
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Immunosuppressive Drugs and Immune Regulation in Organ Transplantation
(Doctoral Thesis)
Sewgobind, V.D.K.D. |
2010-06-08
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Characterization of rabbit antithymocyte globulins-induced CD25+ regulatory T cells from cells of patients with end-stage renal disease
(Article)
Sewgobind, V.D.K.D. Laan, L.J.W. van der Kho, M.M.L. Kraaijeveld, R. Korevaar, S.S. Dam, T. van IJzermans, J.N.M. Weimar, W. Baan, C.C. |
2010-03-01
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End-stage renal failure and regulatory activities of CD4 +CD25bright+FoxP3+ T-cells
(Article)
Hendrikx, T.K. Gurp, E. van Mol, W.M. Schoordijk, W. Sewgobind, V.D.K.D. IJzermans, J.N.M. Weimar, W. Baan, C.C. |
2009-06-01
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The effect of rabbit anti-thymocyte globulin induction therapy on regulatory T cells in kidney transplant patients
(Article)
Sewgobind, V.D.K.D. Kho, M.M.L. Laan, L.J.W. van der Hendrikx, T.K. Dam, T. van Tilanus, H.W. IJzermans, J.N.M. Weimar, W. Baan, C.C. |
2009-05-01
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Conversion from calcineurin inhibitor to mycophenolate mofetil-based immunosuppression changes the frequency and phenotype of CD4+FOXP3+ regulatory T cells
(Article)
Demirkiran, A. Sewgobind, V.D.K.D. Weijde, J. van der Kok, A. Baan, C.C. Kwekkeboom, J. Tilanus, H.W. Metselaar, H.J. Laan, L.J.W. van der |
2009-04-15
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Generation of donor-specific regulatory t-cell function in kidney transplant patients
(Article)
Hendrikx, T.K. Gurp, E. van Baan, C.C. Sewgobind, V.D.K.D. Mol, W.M. Schoordijk, W. Klepper, M. Velthuis, J.H.L. Geel, A. IJzermans, J.N.M. Weimar, W. |
2009-02-15
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Functional analysis of CD4+ CD25 bright T cells in kidney transplant patients: Improving suppression of donor-directed responses after transplantation
(Article)
Sewgobind, V.D.K.D. Laan, L.J.W. van der Klepper, M. IJzermans, J.N.M. Tilanus, H.W. Weimar, W. Baan, C.C. |
2008-10-01
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Interleukin 10: A new risk marker for the development of restenosis after percutaneous coronary intervention
(Article)
Monraats, P.S. Kurreeman, F.A.S. Waltenberger, J. Huizinga, T.W.J. Eefting, D. Quax, P.H.A. Frants, R.R. Laarse, A. van der Wall, E.E. van der Jukema, J.W. Pons, D. Sewgobind, V.D.K.D. Vries, F.R. de Zwinderman, A.H. Maat, M.P.M. de Doevendans, P.A. Winter, R.J. de Tio, R.A. |
2007-01-01
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