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globin expression locus erythroid cells erythroid transcription chromatin region promoter figure signal mouse result level control effect analysis dnase liver number protein transgene histone activation position grosveld hu  promoter - globin locus factor b globin locus deletion probe assay blood liver cells acetylation transcriptional marrow chromatin structure globin genes dnase i sensitivity transcript wijgerde b globin gene development heterochromatin structure tg-hu sensitivity background globin gene expression concentration regulation differentiation γ genes hybridization adult percentage increase dnase i tg-hu  promoter ln 2 hpcs cd 34ϩ cells ach 3 pattern element gene expression suv 39h intron drosophila transcript signals nature bone marrow genes dev globin locus mechanism fication satellite bone marrow cells eklf +/± background
6 Most Recent Publications
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Developmental stage-specific epigenetic control of human beta globin gene expression is potentiated in hematopoietic progenitor cells prior to their transcriptional activation.
(Article)
Bottardi, S. Aumont, A. Grosveld, F.G. Milot, E. |
2003-01-01
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An intrinsic but cell-nonautonomous defect in GATA-1 overexpressing mouse erythroid cells.
(Letter To Editor)
Whyatt, D. Lindeboom, F.A. Karis, A. Milot, E. Bruijn, M.F.T.R. de Langeveld, A. Hendriks, R.W. Gribnau, J.H. Grosveld, F.G. Philipsen, J.N.J. |
2000-08-03
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Activation of the beta β globin locus by transcription factors and chromatin modifiers.
(Article)
McMorrow, T. Wijngaard, A. van den Trimborn, T. Lohuizen, M. van Jenuwein, T. Djabali, M. Philipsen, J.N.J. Fraser, P. Grosveld, F.G. Milot, E. |
2000-01-01
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Chromatin interaction mechanism of transcriptional control in vivo.
(Article)
Gribnau, J.H. Boer, E. de Trimborn, T. Wijgerde, M.G.J.M. Milot, E. Fraser, P. Grosveld, F.G. |
1998-10-15
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The dynamics of gene expression: frequency and duration of transcription.
(Article)
Milot, E. Strouboulis, J. Fraser, P. Trimborn, T. Wijgerde, M.G.J.M. Boer, E. de Langeveld, A. Tan-Un, K. Vergeer, W. Yannoutsos, N. Grosveld, F.G. |
1996-10-01
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Position effects and genetic disease.
(Article)
Milot, E. Fraser, F. Grosveld, F.G. |
1996-04-15
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