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repair ercc 1-xpf 1-xpf ercc 1 dsb repair 165 tor cells patient fi broblasts broblast protein ercc 1ϫ/⌬ mice 86ϫ/ϫ mutation defect hoeijmaker mechanism ercc 1ϫ/ϫ cells endonuclease sensitivity ficiency genetic ercc 1-xpf cells excision group ficient double-strand signi ficantly recombination syndrome overhang nucleotide deletion jaspers ngj patient 165 tor american journal 165 tor plasmid ercc 1ϫ/ϫ mefs cause level cancer signi pathway nucleotide excision repair damage ercc 1 cdna ku 86ϫ/ϫ cells embo j function odijk h ercc 1ϫ/ϫ hoeijmakers jh break allele phenotype jasper table dna-pkc yeast tfiih ercc 1-de mice xeroderma pigmentosum wit j 10-rad rad 10-rad end-joining ku 86 wt cells american nuclease mouse liver complementation ficantly sequence domain appeldoorn e uv-induced uds repair events
3 Most Recent Publications
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Delayed and accelerated aging share common longevity assurance mechanisms
(Article)
Schumacher, B. Pluijm, I. van der Bartke, A. Spindler, S.R. Hoeijmakers, J.H.J. Horst, G.T.J. van der Garinis, G.A. Moorhouse, M.J. Kosteas, T. Robinson, A.R. Suh, Y. Breit, T.M. Steeg, H. van Niedernhofer, L.J. IJcken, W.F.J. van |
2008-08-01
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ERCC1-XPF endonuclease facilitates DNA double-strand break repair
(Article)
Ahmad, R.A. Robinson, A.R. Duensing, A. Drunen, E. van Beverloo, H.B. Weisberg, D.B. Hasty, P. Hoeijmakers, J.H.J. Niedernhofer, L.J. |
2008-08-01
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First reported patient with human ERCC1 deficiency has cerebro-oculo-facio- skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure
(Article)
Jaspers, N.G.J. Raams, A. Vermeulen, W. Silengo, M.C. Wijgers, N. Niedernhofer, L.J. Robinson, A.R. Giglia-Mari, G. Hoogstraten, D. Kleijer, W.J. Hoeijmakers, J.H.J. |
2007-03-01
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