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cancer breast study breast cancer brca 1 patient breast cancer risk carrier association mutation university family genetic tumor analysis research table department disease control variant center institute factor allele group genetics service women hospital expression susceptibility signi centre pathway effect erasmus universiteit rotterdam sample model chemotherapy diagnosis genet kras variant brca 2 carriers population heart status cohort netherland risk factors stage analyses brca 1 carriers oncology result survival subtype number signi ficantly radiotherapy receptor service grant ratio breast cancer res weight treatment rotterdam foundation er-negative genotype heart failure colorectal genome-wide tumor subtypes fi rst-line chemotherapy family history erasmu body weight 1.00 triple-negative breast cancer
10 Most Recent Publications
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Optimal age to start preventive measures in women with BRCA1/2 mutations or high familial breast cancer risk
(Article)
Tilanus-Linthorst, M.M.A. Roozenbeek, B. Eeles, R. Oosterwijk, J.C. Leach, M.O. Steyerberg, E.W. Evans, D.G. Thompson, D. Kaas, R. Manders, P. Asperen, C.J. van Adank, M.A. Hooning, M. Kwan Lim, G.E. |
2013-07-01
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Excess breast cancer risk in first degree relatives of CHEK2* 1100delC positive familial breast cancer cases
(Article)
Adank, M.A. Verhoef, S. Jonker, M.A. Meijers-Heijboer, E.J. Oldenburg, R. Schmidt, M.K. Hooning, M. Martens, J.W.M. Broeks, A. Rookus, M.A. Waisfisz, Q. Witte, B.I. |
2013-05-01
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The risk of primary and contralateral breast cancer after ovarian cancer in BRCA1/BRCA2 mutation carriers: Implications for counseling
(Article)
Vencken, P.M.L.H. Kriege, M. Seynaeve, C.M. Hooning, M. Menke-Pluymers, M.B.E. Heemskerk-Gerritsen, B.A.M. Doorn, L.C. van Collee, J.M. Jager, A. Montfort, C.A.G.M. van Burger, C.W. |
2013-03-01
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Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers
(Article)
Cox, D.G. Simard, J. Szabo, C. Peterlongo, P. Manoukian, S. Bernard, L. Radice, P. Easton, D.F. Antoniou, A.C. Stoppa-Lyonnet, D. Mazoyer, S. Sinilnikova, O. Nordling, M. Greene, M.H. Bergman, A. Einbeigi, Z. Stenmark-Askmalm, M. Liedgren, S. Loman, N. Olsson, H. Kristoffersson, U. Soller, M. Jernström, H. Harbst, K. Mai, P.L. Henriksson, K. Lindblom, A. Arver, B. Wachenfeldt, A. von Liljegren, A. Barbany-Bustinza, G. Rantala, J. Melin, B. Grönberg, H. Stattin, E.-L. Andrulis, I.L. Emanuelsson, M. Ehrencrona, H. Brandell, R.R. Dahl, N. Hogervorst, F.B.L. Verhoef, S. Verheus, M. Leeuwen, F.E. van Collee, J.M. Jager, A. Glendon, G. Hooning, M. Tilanus-Linthorst, M.M.A. Seynaeve, C.M. Wijnen, J.T. Vreeswijk, M.P. Tollenaar, R.A.E.M. Ligtenberg, M. Hoogerbrugge, N. Luijt, R.B. van der Os, T.A.M. van Selander, T. Waisfisz, Q. Meijers-Heijboer, H. Gómez García, E.B. Roozendaal, C.E. van Blok, M.J. Caanen, B. Oosterwijk, J.C. Hout, A.H. van der Mourits, M.J. Vasen, H.F. Weerasooriya, N. Cook, J. Platte, R. Miedzybrodzka, Z. Gregory, H. Morrison, P.J. Jeffers, L. Cole, T.J. Ong, K.R. Hoffman, J. Donaldson, A. Thomassen, M. James, M. Downing, S. Taylor, A. Murray, A. Rogers, M.T. McCann, E. Kennedy, M.J. Barton, D. Porteous, M.E. Drummond, S. Gerdes, A-M. Brewer, C. Kivuva, E. Searle, A. Goodman, S. Hill, K. Davidson, R. Murday, V. Bradshaw, N. Snadden, L. Longmuir, M. Caligo, M.A. Watt, C. Gibson, S. Haque, E. Tobias, E. Duncan, A. Jacobs, C. Langman, C. Whaite, A. Dorkins, H. Barwell, J. Sinnett, D. Friedman, E. Chu, C. Miller, J. Ellis, I.O. Houghton, C. Lalloo, F. Side, L. Male, A. Berlin, C. Collier, R. Douglas, F. Laitman, Y. Claber, O. Jobson, I. Walker, L. McLeod, D. Halliday, D. Durell, S. Stayner, B. Shanley, S. Rahman, N. Houlston, R. Kaufman, B. Bancroft, E. D'Mello, L. Page, E. Ardern-Jones, A. Kohut, K. Wiggins, J. Castro, E. Mitra, A. Robertson, L. Quarrell, O. Paluch, S.S. Bardsley, C. Hodgson, S.V. Goff, S. Brice, G. Winchester, L. Eddy, C. Tripathi, V. Attard, V. Eccles, D. Lucassen, A. Borg, A. Crawford, G. McBride, D. Smalley, S. Léone, M. Buecher, B. Houdayer, C. Belotti, M. Tirapo, C. Pauw, A. de Bressac-de Paillerets, B. Karlsson, P. Remenieras, A. Byrde, V. Lenoir, G.M. Bignon, Y.-J. Uhrhammer, N. Bonadona, V. Bourdon, V. Noguchi, T. Coulet, F. Colas, C. Askmalm, M.S. Soubrier, F. Coupier, I. Pujol, P. Peyrat, J.-P. Fournier, J. Révillion, F. Vennin, P. Adenis, C. Ouweland, A.M.W. van den Rouleau, E. Bustinza, G.B. Lidereau, R. Demange, L. Nogues, C. Muller, D.W. Fricker, J.P. Longy, M. Sevenet, N. Toulas, C. Guimbaud, R. Gladieff, L. Nathanson, K.L. Feillel, V. Leroux, D. Dreyfus, H. Rebischung, C. Coron, F. Faivre, L. Prieur, F. Lebrun, M. Ferrer, S.F. Frenay, M. Domchek, S.M. Vénat-Bouvet, L. Asperen, C.J. van Veer, L.J. van 't Hamdi, Y. Rebbeck, T.R. Benitez, J. Hamann, U. Rookus, M.A. Ausems, M.G.E.M. Aalfs, C. Devilee, P. Gille, H.J.J.P. Peock, S. Frost, D. Soucy, P. Evans, D.G. Eeles, R. Izatt, L. Adlard, L. Paterson, J. Eason, J. Godwin, A.K. Remon, M.-A. Moncoutier, V. Gauthier-Villars, M. Ouimet, M. Lassett, C. Giraud, S. Hardouin, A. Berthet, P. Sobol, H. Eisinger, F. Paillerets, B.B. de Caron, O. Delnatte, C.D. Goldgar, D. Barjhoux, L. Miron, A. Ozcelik, H. Buys, S.S. Southey, M.C. Terry, M-B. Singer, C.F. Dressler, C. Tea, M.-K. Hansen, T.V.O. Johannsson, O.T. Verny-Pierre, C. Piedmonte, M. Rodriguez, G.C. Basil, J. Blank, S.V. Toland, A.E. Montagna, M. Isaacs, C. Blanco, I. Gayther, S.A. Moysich, K.B. McGuffog, L. Schmutzler, R.K. Wappenschmidt, B. Engel, C. Meindl, A. Ditsch, N. Arnold, N. Niederacher, D. Sutter, C. Gadzicki, D. Fiebig, B. Healey, S. Caldes, T. Laframboise, R. Nevanlinna, H. Chenevix-Trench, G. Beesley, J. Spurdle, A.B. Neuhausen, S.L. Ding, Y.C. Couch, F.J. Wang, X. |
2011-12-01
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Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
(Article)
Antoniou, A.C. kartsonaki, C. Zaffaroni, D. Hopper, J. Daly, M. Terry, M-B. John, E.M. Buys, S.S. Yassin, Y. Miron, A. Goldgar, D. Singer, C.F. Tea, M.-K. Cattaneo, E. Pfeiler, G. Dressler, C. Hansen, T.V.O. Jønson, L. Ejlertsen, B. Barkardottir, R.B. Kirchhoff, T. Offit, K. Piedmonte, M. Rodriguez, G.C. Barile, M. Small, L. Boggess, J.F. Blank, S.V. Basil, J. Azodi, M. Toland, A.E. Montagna, M. Tognazzo, S. Agata, S. Imyanitov, E.N. Pensotti, V. Janavicius, R. Lazaro, C. Blanco, I. Pharoah, P.D.P. Sucheston, L. Karlan, B.Y. Walsh, C.S. Olah, E. Bozsik, A. Teo, S.-H. Pasini, B. Seldon, J.L. Beattie, M.S. Rensburg, E.J. van Sluiter, M.D. Diez, O. Schmutzler, R.K. Wappenschmidt, B. Engel, C. Meindl, A. Ruehl, I. Dolcetti, R. Varon-Mateeva, R. Kast, K. Deissler, H. Niederacher, D. Arnold, N. Gadzicki, D. Schönbuchner, I. Caldes, T. Hoya, M. de La Nevanlinna, H. Giannini, G. Aittomäki, K. Dumont, M. Chiquette, J. Tischkowitz, M. Chenevix-Trench, G. Beesley, J. Spurdle, A.B. Neuhausen, S.L. Ding, Y.C. Fredericksen, Z. Putignano, A.L. Wang, X. Pankratz, V.S. Couch, F.J. Simard, J. Easton, D.F. Chenevix-Trench, G. Karlsson, P. Nordling, M. Bergman, A. Einbeigi, Z. Varesco, L. Stenmark-Askmalm, M. Liedgren, S. Borg, A. Olsson, H. Kristoffersson, U. Jernström, H. Henriksson, K. Wachenfeldt, A. von Liljegren, A. Barbany-Bustinza, G. Radice, P. Rantala, J. Grönberg, H. Stattin, E.-L. Emanuelsson, M. Brandell, R.R. Dahl, N. Verhoef, S. Verheus, M. Veer, L.v. Leeuwen, F.E. van Sinilnikova, O. Mai, P.L. Collee, J.M. Ouweland, A.M.W. van den Jager, A. Tilanus-Linthorst, M.M.A. Seynaeve, C.M. Wijnen, J.T. Vreeswijk, M.P. Tollenaar, R.A.E.M. Ligtenberg, M. Hoogerbrugge, N. Greene, M.H. Ausems, M.G.E.M. Aalfs, C. Gille, J.J.P. Waisfisz, Q. Gómez García, E.B. Roozendaal, C.E. van Blok, M.J. Caanen, B. Oosterwijk, J.C. Hout, A.H. van der Andrulis, I.L. Mourits, M.J. Vasen, H.F. Gregory, H. Morrison, P.J. Jeffers, L. Cole, T.J. McKeown, C. Hoffman, J. Donaldson, A. Downing, S. Glendon, G. Taylor, A. Murray, A. Rogers, M.T. McCann, E. Porteous, M.E. Drummond, S. Brewer, C. Kivuva, E. Searle, A. Goodman, S. Ozcelik, H. Hill, K. Murday, V. Bradshaw, N. Snadden, L. Longmuir, M. Watt, C. Gibson, S. Haque, E. Tobias, E. Duncan, A. Thomassen, M. Jacobs, C. Langman, C. Whaite, A. Dorkins, H. Barwell, J. Chu, C. Miller, J. Ellis, I.O. Houghton, C. Side, L. Gerdes, A-M. Male, A. Berlin, C. Eason, J. Collier, R. Claber, O. Jobson, I. Walker, L. McLeod, D. Halliday, D. Durell, S. Kruse, T.A. Stayner, B. Shanley, S. Rahman, N. Houlston, R. Bancroft, E. D'Mello, L. Page, E. Ardern-Jones, A. Kohut, K. Wiggins, J. Jensen, U.B. Castro, E. Mitra, A. Robertson, L. Quarrell, O. Bardsley, C. Hodgson, S.V. Barton, D.E. Goff, S. Brice, G. Winchester, L. Cruger, D. Eddy, C. Tripathi, V. Attard, V. Lucassen, A. Crawford, G. McBride, D. Smalley, S. Adlard, J.W. Arver, B. Soucy, P. Caligo, M.A. Laitman, Y. Milgrom, R. Kaufman, B. Paluch-Shimon, S. Friedman, E. Loman, N. Harbst, K. Lindblom, A. Ehrencrona, H. McGuffog, L. Melin, B. Nathanson, K.L. Domchek, S.M. Rebbeck, T.R. Jakubowska, A. Lubinski, J. Gronwald, J. Huzarski, T. Byrski, T. Cybulski, C. Healey, S. Górski, B. Osorio, A. Cajal, T.R. Fostira, F. Andres, R. Benitez, J. Hamann, U. Hogervorst, F.B.L. Rookus, M.A. Hooning, M. Lee, A. Nelen, M.R. Luijt, R.B. van der Os, T.A.M. van Asperen, C.J. van Devilee, P. Meijers-Heijboer, H. Garcia, E.B.G. Peock, S. Cook, M. Frost, D. Peterlongo, P. Platte, R. Leyland, J. Evans, D.G. Lalloo, F. Eeles, R. Izatt, L. Davidson, R. Eccles, D. Ong, K.-R. Douglas, F. Manoukian, S. Paterson, J. Kennedy, M.J. Miedzybrodzka, Z. Godwin, A.K. Stoppa-Lyonnet, D. Buecher, B. Belotti, M. Tirapo, C. Mazoyer, S. Barjhoux, L. Peissel, B. Lassett, C. Leroux, D. Faivre, L. Bronner, M. Prieur, F. Nogues, C. Rouleau, E. Pujol, P. Coupier, I. Frenay, M. |
2011-08-01
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Prevalence of the variant allele rs61764370 T>G in the 3′UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families
(Article)
Hollestelle, A. Pelletier, C. Aulchenko, Y.S. Martens, J.W.M. Ouweland, A.M.W. van den Weidhaas, J. Hooning, M. Crepin, E. Schutte, A.E.M. Look, M.P. Collée, J.M. Nieuwlaat, A. Dorssers, L.C.J. Seynaeve, C.M. |
2011-07-01
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Chemosensitivity and outcome of BRCA1- and BRCA2-associated ovarian cancer patients after first-line chemotherapy compared with sporadic ovarian cancer patients
(Article)
Vencken, P.M.L.H. Kriege, M. Seynaeve, C.M. Hoogwerf, D. Beugelink, S. Burg, M.E.L. van der Hooning, M. Berns, P.M.J.J. Jager, A. Collée, J.M. Burger, C.W. |
2011-06-06
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A 3'-untranslated region KRAS variant and triple-negative breast cancer: A case-control and genetic analysis
(Article)
Paranjape, T. Heneghan, H. Martens, J.W.M. Hooning, M. Kerin, M. Zelterman, D. Zhu, Y. Tuck, D. Harris, L. Miller, N. Slack, F. Weidhaas, J. Lindner, R. Keane, F.K. Hoffman, A. Hollestelle, A. Dorairaj, J. Geyda, K. Pelletier, C. Nallur, S. |
2011-04-01
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A combined analysis of genome-wide association studies in breast cancer
(Article)
Li, J. Humphreys, M.K. Ouweland, A.M.W. van den Alfredsson, L. Palotie, A. Peltonen-Palotie, L. Irwanto, A. Low, H.Q. Teoh, G.H.K. Thalamuthu, A. Easton, D.F. Nevanlinna, H. Heikinen, T. Liu, J. Czene, k. Hall, A.S. Aittomäki, K. Blomqvist, C. Pharoah, P.D.P. Dunning, A.M. Ahmed, S. Hooning, M. Martens, J.W.M. |
2011-04-01
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Associations of breast cancer risk factors with tumor subtypes: A pooled analysis from the breast cancer association consortium studies
(Article)
Yang, X.R. Chang-Claude, J. Fasching, P.A. Shen, C.-Y. Hsiung, C.-N. Wu, P.E. Yu, J.-C. Chen, S.-T. Hsu, G.-C. Haiman, C.A. Henderson, B.E. Le Marchand, L. Kolonel, L.N. Hein, R. Lindblom, A. Margolin, S. Jakubowska, A. Lubinski, J. Huzarski, T. Byrski, T. Górski, B. Gronwald, J. Hooning, M. Hollestelle, A. Spurdle, A.B. Ouweland, A.M.W. van den Jager, A. Kriege, M. Tilanus-Linthorst, M.M.A. Collee, J.M. Wang-Gohrke, S. Pylkäs, K. Jukkola-Vuorinen, A. Mononen, K. Grip, M. Blows, F. Hirvikoski, P. Winqvist, R. Mannermaa, A. Kosma, V.M. Kauppinen, J. Kataja, V. Auvinen, P. Soini, Y. Sironen, R. Bojesen, S.E. Driver, K. Dynnes Ørsted, D. Kaur-Knudsen, D. Flyger, H. Nordestgaard, B.G. Holland, H. Chenevix-Trench, G. Manoukian, S. Barile, M. Radice, P. Hankinson, S.E. Flesch-Janys, D. Hunter, D. Tamimi, R. Sangrajrang, S. Brennan, P. McKay, J. Odefrey, F. Gaborieau, V. Devilee, P. Huijts, P. Tollenaar, R. Heinz, J. Seynaeve, C.M. Dite, G.S. Apicella, C. Hopper, J. Hammet, F. Tsimiklis, H. Smith, L. Southey, M.C. Easton, D.F. Pharoah, P. Sinn, P. Sherman, M. García-Closas, M. Vrieling, A. Heikinen, T. Goode, E.L. Aittomäki, K. Heikkilä, P. Blomqvist, C. Lissowska, J. Peplonska, B. Chanock, S.J. Figueroa, J. Brinton, L.A. Hall, A.S. Czene, k. Couch, F.J. Humphreys, M.K. Darabi, H. Liu, J. Veer, L.J. van 't Leeuwen, F.E. van Andrulis, I.L. Glendon, G. Knight, J.A. Mulligan, A.M. O'Malley, F.P. Nevanlinna, H. Weerasooriya, N. John, E.M. Beckmann, M.W. Hartmann, A. Weihbrecht, S.B. Wachter, D.L. Jud, S.M. Loehberg, C.R. Baglietto, L. English, D.R. Milne, R.L. Giles, G.G. McLean, C.A. Severi, G. Lambrechts, D. Vandorpe, T. Weltens, C. Paridaens, R. Smeets, A. Neven, P. Wildiers, H. Gaudet, M.M. Wang, X. Olson, J.E. Cafourek, V. Fredericksen, Z. Kosel, M. Vachon, C. Cramp, H.E. Connley, D. Cross, S.S. Balasubramanian, S. Schmidt, M.K. Reed, M.W.R. Dörk, T. Bremer, M. Meyer, A. Karstens, J.H. Ay, A. Park-Simon, T.-W. Hillemanns, P. Arias Pérez, J.I. Rodríguez, P.M. Broeks, A. Zamora, P. Benitez, J. Ko, Y.D. Fischer, H.-P. Hamann, U. Pesch, B. Brüning, T. Justenhoven, C. Brauch, H. Eccles, D. Cox, A. Tapper, W. Gerty, S.M. Sawyer, E.J. Tomlinson, I.P. Jones, A. Kerin, M. Miller, N. McInerney, N. Anton-Culver, H. Ziogas, A. |
2011-02-02
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