Sijbers, A.M.

protein repair ercc 1 ercci domain mutation residue group patient sequence binding excision damage ercc 1 protein tibolone interaction activity incision region ercc 1xpf nucleotide recombination c-terminal hoeijmaker xeroderma analysis xpf protein fragment antibody homolog nucleotide excision repair pigmentosum figure lesion endonuclease transcription motif effect level cancer product process sancar formation position expression factor amount strand acids research function polymerase yeast chapter result defect ercci-xpf number nuclease syndrome complementation reaction cross-link cell lines pathway extract cell extracts synthesis mutant ercci protein homology fraction rodent 43-3 erccl point clone hhh motif ercc 1-binding domain structure