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scopus: 7101744910

Miedema, F.

(Frank Miedema)


patient ebv-specific ebv load number infection t cells virus t-cell ebv reactivation response study blood individual tetramer figure reactivation aids-nhl epstein-barr assay lymphocytes epstein-barr virus analysis ebv-specific t cells time point point epitope ebv-lpd progressor tetramer t cells function cytotoxic month aids-nhl patients control gag-specific recipient gag-specific ctl responses lytic elispot assay disease time points j exp med staining level course percentage lymphoma recovery follow-up value sample immunodeficiency count panel increase peptide tetramer staining transplantation 1000 geq /ml elispot donor lymphoproliferative serum hiv infection 6 months subject result hiv-infected individuals group diagnosis t cell function progression graft cell transplantation hiv individuals j virol antigen seroconversion development range




5 Most Recent Publications

Impaired recovery of Epstein-Barr virus (EBV)--specific CD8+ T lymphocytes after partially T-depleted allogeneic stem cell transplantation may identify patients at very high risk for progressive EBV reactivation and lymphoproliferative disease (Article)
Meij, P. Löwenberg, B. Leiner, I. Pamer, E. Gratama, J-W. Cornelissen, J.J. Esser, J.W.J. van Niesters, H.G.M. Baarle, D. van Miedema, F. Blake, N. Rickinson, A.B.
2003-01-01
Absolute level of Epstein-Barr Virus (EBV) DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma. (Article)
Baarle, D. van Wolthers, K.C. Hovenkamp, E. Osterhaus, A.D.M.E. Miedema, F. Oers, M.H.J. van Niesters, H.G.M.
2002-08-01
Dysfunctional Epstein-Barr virus (EBV)-specific CD8(+) T lymphocytes and increased EBV load in HIV-1 infected individuals progressing to AIDS-related non-Hodgkin lymphoma (Article)
Baarle, D. van Miedema, F. Oers, M.H.J. van Hovenkamp, E. Callan, M.F.C. Wolthers, K.C. Kostense, S. Tan, L.C. Niesters, H.G.M. Osterhaus, A.D.M.E. McMichael, A.J.
2001-01-01
Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: A longitudinal analysis of rapid progressors and long-term asymptomatics. (Article)
Klein, M.R. Baalen, C.A. van Holwerda, A.M. Kerkhof Garde, S.R. Bende, R.J. Keet, I.P.M. Eeftinck-Schattenkerk, J-K.M. Osterhaus, A.D.M.E. Schuitemaker, H. Miedema, F.
1995-01-01
Selective in vitro expansion of HLA class I-restricted HIV-1 gag-specific CD8+ T cells: cytotoxic T-lymphocyte epitopes and precursor frequencies. (Article)
Baalen, C.A. van Klein, M.R. Geretti, A.M. Keet, R.I.P.M. Miedema, F. Els, C.A.C.M. van Osterhaus, A.D.M.E.
1993-01-01