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trpv 5ϫ/ϫ mice trpv 5−/− mice expression zk 191784 trpv 5 level alendronate 5−/− effect control protein osteoclast calbindin-d kidney trpv 6 transport channel serum treatment 2ϩ absorption resorption 5+/+ 2ϩ transport proteins transporter culture ohase trpv 5+/+ mice 1␣- analysis epithelial absorption wt mice bindel 2ϩ excretion hoenderop 2ϩ transport alendronate treatment study van der kemp 2ϩ reabsorption vitamin analog signi ficantly 2ϩ uptake trpv 5ϫ/ϫ/1␣-ohase mice trpv 5ϩ/ϩ controls excretion animal thickness 0.1 figure hyperabsorption bone thickness trpv 5+/+ 2ϩ transporters trpv 5+/+ controls bone resorption 2ϩ hyperabsorption hoenderop jg bindels rj vacuolar h +-atpase radboud university nijmegen wild-type mice knockout 0.05 mrna expression signi vehicle reabsorption ficantly urine 28 days concentration nijmegen membrane uptake homeostasi zk 191784 treatment wild-type 2ϩ transporter expression
3 Most Recent Publications
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Bone resorption inhibitor alendronate normalizes the reduced bone thickness of TRPV5-/- mice
(Article)
Nijenhuis, T. Eerden, B.C.J. van der Hoenderop, J.G.J. Weinans, H.H. Leeuwen, J.P.T.M. van Bindels, R.J.M. |
2008-11-01
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The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist
(Article)
Nijenhuis, T. Eerden, B.C.J. van der Zügel, U. Steinmeyer, A. Weinans, H.H. Hoenderop, J.G.J. Leeuwen, J.P.T.M. van Bindels, R.J.M. |
2006-10-01
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Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice
(Article)
Renkema, K.Y. Nijenhuis, T. Eerden, B.C.J. van der Kemp, A.W.C.M. Weinans, H.H. Leeuwen, J.P.T.M. van Bindels, R.J.M. Hoenderop, J.G.J. |
2005-11-01
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