Lynch, T.W.

protein filament binding atpase structure i 345t ssdna rad 51 h 352 figure hydrolysis atp hydrolysis r 357 activity presence reaction residue atpase site scrad assay acids research crystal r 357m protomer interface absence strand-exchange strand helix atpase activity dna binding dsdna filter substrate rad 51 protein cofactor domain nucleotide scrad 51 nucleotide cofactor mutation mvrada amppnp research ssdna binding 1 mm dtt wt rad 51 strand exchange mutant wt protein double-stranded dna function rad 51 proteins control interaction exchange contact 308 c variant crystal structures condition atp binding image strand-exchange reactions k 191r yeast r 357 mutants formation filter binding assays experiment wt scrad 51 pdbid result 3 rd phosphate 5 mm atp escherichia coli reca atpase assays recombination loop 2 figure 3