Zwaan, C.M.

myelomonocytic leukemia mutation leukemia myelomonocytic syndrome pathway nf 1 gene ras pathway patient noonan syndrome blood jmml patients noonan children niemeyer cm protein activation figure castleberry rp analysis childhood br j haematol haematologica neurofibromatosi niemeyer c-cbl emanuel pd myelodysplastic syndromes myelodysplastic gm-csf result study treatment emanuel thrombosis nat genet erasmus mc flt 3 mutations hypersensitivity ptpn 11 cell transplantation ptpn 11 gene function monosomy 7 myeloid kratz cp monosomy ewog-md aberration kratz pten protein deficiency transplantation pathogenesis flotho malignancy factor group castleberry michael zwaan treatment option vries ac leiden university response oncology /hematology pediatr steinemann germline european leiden gm-csf hypersensitivity event sakai ds inactivation jmml patient p 13k thomas c nf 1. van wering editorial growth