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dai: 298677660
scopus: 7004732600

Staal, F.J.T.

(Frank Staal)


development thymocyte t cell development protein expression rearrangement stage factor differentiation transcription target catenin wnt target genes notch t cells analysis signal target genes level cd 34 thymocytes thymu microarray control family block proliferation immunol t cell differentiation lineage pathway binding e proteins transcriptional induction cluster regulation cl 100 phosphatase experiment staal class transduction lymphoid study promoter receptor wnt signals function thymic downloaded kinase probe rq-pcr fibronectin clever j rearrangements thymocyte development treatment recombination mouse defect member ikaro cd 34 subset e 2a mice phosphatase activity activation enhancer nature wnt / gata -3 langerak november selection thymocyte differentiation t cell lineage t lymphocyte differentiation lymphocyte www.stemcells.com




10 Most Recent Publications

Combined TCRG and TCRA TREC analysis reveals increased peripheral T-lymphocyte but constant intra-thymic proliferative history upon ageing (Article)
Weerd, K. van der Dik, W.A. Schrijver, B. Bogers, A.J.J.C. Maat, A.W.P.M. Nederveen, F.H. van Hagen, P.M. van Dongen, J.J.M. van Langerak, A.W. Staal, F.J.T.
2013-03-01
Morbidly obese human subjects have increased peripheral blood CD4 + T cells with skewing toward a Treg- and Th2-dominated phenotype (Article)
Weerd, K. van der Dik, W.A. Lelij, A.J. van der Staal, F.J.T. Hagen, P.M. van Schrijver, B. Schweitzer, D.H. Langerak, A.W. Drexhage, H.A. Kiewiet-Kemper, R.M. Aken, M.O. van Huisstede, A. van Dongen, J.J.M. van
2012-02-01
Signal transduction pathways regulating hematopoietic stem cell biology: Introduction to a series of Spotlight Reviews (Article)
Luis, T.C. Killmann, N.M.B. Staal, F.J.T.
2012-01-01
Correction of murine Rag1 deficiency by self-inactivating lentiviral vector-mediated gene transfer (Article)
Pike-Overzet, K. Rodijk, M. Bredius, R.G.M. Driessen, G.J.A. Thrasher, A.J. Baum, J.A.C. Cavazzana-Calvo, M. Dongen, J.J.M. van Staal, F.J.T. Ng, Y.Y. Baert, M.R. Lagresle-Peyrou, C. Schambach, A. Zhang, F. Hoeben, R.C. Hacein-Bey-Abina, S. Lankester, A.C.
2011-09-01
Effective treatment of psoriasis with narrow-band UVB phototherapy is linked to suppression of the IFN and Th17 pathways (Article)
Rácz, E. Prens, E.P. Staal, F.J.T. Fits, L. van der Kurek, D.M. Kant, M. Ridder, D. de Mourits, S. Baerveldt, E.M. Özgür, Z. IJcken, W.F.J. van Laman, J.D.
2011-07-01
Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia (Article)
Homminga, I. Pieters, R. Vlierberghe, P. van Ferrando, A.A. Cayuela, J.M. Verhaaf, B. Beverloo, H.B. Horstmann, M. Haas, V. de Wiekmeijer, A.-S. Pike-Overzet, K. Staal, F.J.T. Langerak, A.W. Laat, W.L. de Soulier, J. Sigaux, F. Meijerink, J.P.P. Rooi, J.J. de Stubbs, A. Verstegen, M.M.A. Vuerhard, M.J. Buijs-Gladdines, J.G.C.A.M. Kooi, C. Klous, P.
2011-04-12
Correction of B-cell development in Btk-deficient mice using lentiviral vectors with codon-optimized human BTK (Article)
Ng, Y.Y. Baert, M.R. Pike-Overzet, K. Rodijk, M. Brugman, M.H. Schambach, A. Hendriks, R.W. Dongen, J.J.M. van Staal, F.J.T.
2010-09-01
Detection of fusion genes at the protein level in leukemia patients via the flow cytometric immunobead assay (Article)
Dekking, E. Velden, V.H.J. van der Kalina, T. Kovac, M. Evans, P. Hoogeveen, P.G. Flores-Montero Orfao, A. Comans-Bitter, W.M. Staal, F.J.T. Dongen, J.J.M. van Böttcher, S. Brüggemann, M. Sonneveld, E. Koning-Goedheer, A. Boeckx, N. Lucio, P. Sedek, L. Szczepański, T.
2010-09-01
Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling (Article)
Luis, T.C. Naber, B.A.E. Fibbe, W.E. Dongen, J.J.M. van Staal, F.J.T.
2010-07-01
Wnt signaling in hematopoiesis: Crucial factors for self-renewal, proliferation, and cell fate decisions (Article)
Staal, F.J.T. Luis, T.C.
2010-04-01