Schiphof, D.

study osteoarthritis grade criteria knee oa cartilage classi fication criteria description association knee osteoarthritis osteophyte classi knee pain population fication alternative radiographic score risk factors women rheum feature radiological cartilage volume radiograph shape factor article k &l criteria chapter knee complaints classification volume table medial lesion complaint symptom cohort space result arthritis presence participant determinant kellgren difference analysis lawrence evidence rotterdam study cartilage defects change oestrogen ann rheum dis study population rotterdam radiographic knee oa bone marrow lesions value reliability defect kappa system prevalence impact assessment osteoarthritis cartilage research disease tibial classification criteria medial tibia method validity tibia felson k &l grades compartment severity