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expression thymocyte development gata 3 differentiation cd 2-gata catenin level wnt 3a rearrangement gata 3 expression analysis stage 2-gata t cell development immunol culture factor number target wnt target genes subset 17 differentiation transcription 17 cells wnt 3a embryos il -4 17 cultures - catenin protein thymic thymu induction cd 34 thymocytes embryo production t cells cytokine experiment target genes presence microarray blood signal proliferation mouse figure 0.0 capacity percentage pathway thymocyte subsets effect wnt signals ficiency hematopoietic wnt 3a cells assay rq-pcr cluster t-cell cl 100 phosphatase study result information fig progenitors wnt 3a fls antibody il -17-producing cells flow cytometric analysis fl ow cytometry transduction il -171 cells progenitor intracellular probe 1.0 control clever transplantation
6 Most Recent Publications
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Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
(Article)
Luis, T.C. Weerkamp, F. Naber, B.A. Baert, M.R. Haas, E.F. de Nikolic, T. Heuvelmans, S. Krijger, R.R. de Dongen, J.J.M. van Staal, F.J.T. |
2009-01-15
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Isolation of human and mouse hematopoietic stem cells.
(Article)
Ng, Y.Y. Baert, M.R. Haas, E.F. de Pike-Overzet, K. Staal, F.J.T. |
2009-01-01
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Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology
(Article)
Hamburg, J.P. van Bruijn, M.J.W. de Ribeiro de Almeida, C. Zwam, M. van Meurs, M. van Haas, E.F. de Boon, L. Samsom, J.N. Hendriks, R.W. |
2008-09-01
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Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules.
(Article)
Weerkamp, F. Baert, M.R. Naber, B.A. Koster, E.E. Haas, E.F. de Atkuri, K.R. Dongen, J.J.M. van Herzenberg, L.A. Staal, F.J.T. |
2006-02-28
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New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling
(Article)
Dik, W.A. Dongen, J.J.M. van Spek, P.J. van der Pike-Overzet, K. Staal, F.J.T. Langerak, A.W. Weerkamp, F. Ridder, D. de Haas, E.F. de Baert, M.R. Koster, E.E. Reinders, M.J. |
2005-01-01
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Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion
(Article)
Staal, F.J.T. Weerkamp, F. Baert, M.R. Burg, C.M. van den Noort, M. van Haas, E.F. de Dongen, J.J.M. van |
2004-01-01
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