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thyroid hormone serum level effect activity liver patient plasma uptake polymorphism study subject triac concentration deiodinase incubation release endocrinol table medium endocrinology allele metabolism protein iodothyronine thyroid hormone library erasmus mc ratio population value thyroid hormone metabolism analysis 1 activity tetrac tsh release sult 1e metab visser 3 activity insulin downloaded haplotype result muscle tissue experiment expression igf-i e 2 sulfation culture correlation fraction deiodination trh-induced tsh release netherland sulfation parameter journal variant infusion serum t 3 production association control treatment rt 3 levels erasmu receptor presence fasting illness culture medium blood enzyme serum thyroid parameters incubation medium change insulin resistance 3 days
10 Most Recent Publications
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Thyroid status in a large cohort of patients with mental retardation: The TOP-R (Thyroid Origin of Psychomotor Retardation) study
(Article)
Visser, W. Rijke, Y.B. de Toor, H. van |
2011-09-01
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Mutations in the iodotyrosine deiodinase gene and hypothyroidism
(Article)
Moreno, J.C. Klootwijk, W. Toor, H. van Pinto, G. D'Alessandro, M. Lèger, A. Goudie, D. Polak, M.G. Grüters, A. Visser, T.J. |
2008-04-24
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The Asp727Glu polymorphism in the TSH receptor is associated with insulin resistance in healthy elderly men
(Article)
Peeters, R.P. Deure, W.M. van der Beld, A.W. van den Toor, H. van Lamberts, S.W.J. Janssen, J.A.M.J.L. Uitterlinden, A.G. Visser, T.J. |
2007-06-01
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Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities.
(Article)
Peeters, R.P. Wouters, P.J. Toor, H. van Kaptein, E. Visser, T.J. Berghe, G. van den |
2005-08-01
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A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters.
(Article)
Peeters, R.P. Beld, A.W. van den Attalki, H. Toor, H. van Rijke, Y.B. de Kuiper, G.G.J.M. Lamberts, S.W.J. Janssen, J.A.M.J.L. Uitterlinden, A.G. Visser, T.J. |
2005-07-01
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A polymorphism in type I deiodinase is associated with circulating free insulin-like growth factor I levels and body composition in humans.
(Article)
Peeters, R.P. Beld, A.W. van den Toor, H. van Uitterlinden, A.G. Janssen, J.A.M.J.L. Lamberts, S.W.J. Visser, T.J. |
2005-01-01
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Molecular basis for the substrate selectivity of cat type I iodothyronine deiodinase.
(Article)
Kuiper, G.G.J.M. Wassen, F.W. Klootwijk, W. Toor, H. van Kaptein, E. Visser, T.J. |
2003-12-01
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Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects
(Article)
Peeters, R.P. Toor, H. van Klootwijk, W. Rijke, Y.B. de Uitterlinden, A.G. Visser, T.J. Kuiper, G.G.J.M. |
2003-01-01
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Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients
(Article)
Peeters, R.P. Wouters, P.J. Kaptein, E. Toor, H. van Visser, T.J. Berghe, G. van den |
2003-01-01
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Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters
(Article)
Kester, M.H.A. Visser, T.J. Brouwer, A. Bulduk, S. Toor, H. van Tibboel, D. Meinl, W. Glatt, H. Falany, C.N. Coughtrie, M.W. Schuur, A.G. |
2002-01-01
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