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tuberin protein hamartin neuron binding domain figure interaction rab 4 recycling gst -14-3-3 beads endosome antibody endosomal transfected beads lysate hippocampal syntaxin spine zwint rab 3c membrane syntaxin 13 hippocampal neurons receptor expression tuberin-hamartin control assay 10 mm gfp-rab -14-3-3 image ampar 14-3-3 div 13 dendrite colocalization structure tsc 1 rab 11 domains cos -7 cells synaptic mouse localization two-hybrid yeast gfp-rab 4 isoform hela cells rab 11 variant -1-shrna fraction buffer erasmus mc hippocampal neurons cotransfected hippocampal neurons transfected dendritic cell body fluorescence representative images analysis trafficking 10 min function surface result 4 ° c experiment myc-grasp volume coiled-coil biology fusion pathway effector recycling endosomes psuper control vector
5 Most Recent Publications
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Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes
(Article)
Hoogenraad, C.C. Popa, I. Heck, A.J.R. Sheng, M. Klumperman, J. Rehmann, H. Jaarsma, D. Kapitein, L.C. Sluijs, P. van der Futai, K. Sanchez-Martinez, E. Wulf, P. Vlijmen, T. van Dortland, B.R. Oorschot, V. Govers, R. Monti, M. |
2010-01-01
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A unique residue in rab3c determines the interaction with novel binding protein Zwint-1
(Article)
Vlijmen, T. van Vleugel, M. Evers, M. Mohammed, S. Wulf, P. Heck, A.J.R. Hoogenraad, C.C. Sluijs, P. van der |
2008-08-20
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Identification and characterization of the interaction between tuberin and 14-3-3zeta.
(Article)
Nellist, M.D. Goedbloed, M.A. Winter, C. de Verhaaf, B. Jankie, A. Reuser, A.J.J. Ouweland, A.M.W. van den Sluijs, P. van der Halley, D.J.J. |
2002-10-18
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Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin
(Article)
Nellist, M.D. Slegtenhorst, M.A. van Ouweland, A.M.W. van den Halley, D.J.J. Sluijs, P. van der Goedbloed, M.A. |
1999-01-01
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Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products
(Article)
Nellist, M.D. Nagelkerken, B. Cheadle, J. Snell, R. Sampson, J. Sluijs, P. van der Halley, D.J.J. Ouweland, A.M.W. van den Reuser, A.J.J. Slegtenhorst, M.A. van |
1998-01-01
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