Kuypers, D.

patient transplantation transplant exposure study concentration mpa exposure mycophenolate mycophenolate mofetil recipient mycophenolic acid mycophenolic rejection tacrolimu mofetil transplant recipients pharmacokinetic month liver group drug monitoring monitoring kidney effect therapy plasma cyclosporine trial incidence polymorphism relationship cyp 3a dosing target point university analysis ec-mp cyp 3a genotype enteric-coated mycophenolate sodium mpa-auc mpa concentrations liver transplantation department outcome difference mpa auc 0–12 liver transplant recipients strategy sampling value graft function time points van gelder t method roche range result metabolite 0–12 adult mpa-auc 0 –12 mycophenolic acid exposure day 3 glucuronide table cyp 3a expressers mpa c 0 genotype gelder assay variability mmf dose trough diarrhea regimen randomized event heart