Gurp, E. van

patient 25bright t cells transplantation cd 25bright cells level study expression t-cell function il -2 number blood transplant kidney effect analysis treatment cp -690 550 -690 serum proliferation foxp 3 control sample allograft response capacity p-stat immunol 25neg esrf patients result 25+ rapamycin p-stat 5 levels dialysis recipient tacrolimu suppressive presence depletion lymphocyte kidney transplant patients rejection figure baseline increase production month inhibition bd biosciences inhibitor day 1 table donor cd 4ϩcd t-cells day 29 fraction suppressive function cd 25neg cells il -2 production population change kidney transplant recipients subset cohort monotherapy stimulation organ pathway rotterdam group count 30 mg bid proliferative response erasmus university rotterdam tolerance disease cd 4ϩcd cells