Arkel, C. van

c 57bl mice group b-cell antibody mouse development clone study response incidence b cells tg mice chapter serum myeloma control disorder immunoglobulin antigen antibody response level b-cell proliferative disorders lineage sequence mutation frequency isotype origin number clonal proliferative allotype b -2 cells model clonal dominance disease category radl j component system table experiment treatment month strain effect lm mice result animal bm cells lymphoma plasma tumor immunization t-cell expression chimera difference population age-related herzenberg cell population analysis blood dominance antigenic stimulation mechanism antigenic patient gammopathie c 57bl cba mice survival protein region dnp-hsa precursor h-ig components transplantation cell lineage