Emmerik, N.E.M. van

donor avidity rejection class avidity ctl donor ag graft allograft transplant clone t cells antigen molecule target transplantation patient culture study target cells cytotoxic transplant rejection frequency lymphocytes heart interaction blood allograft rejection activation peptide number gil cultures expression result response donor class ii ctl clones cytokine figure analysis production anti-cd rejection episode rejection status observation rejection therapy stimulation presence cd 8+t cells cytotoxicity period fraction receptor donor cells sample status t cell activation heart transplant recipients mhc class i surface 2 weeks effector profile heart transplant patients cd 8 mab immunol antibody recipient emmerik /peptide avidity pctl addition chapter t cell b-lcl avidity cd 4 binding affinity model blood samples lymphocyte