Kesteren, C.A.M. van

renin prorenin receptor angiotensin medium effect ang ii phosphate tissue fibroblast incubation heart activation binding cardiomyocyte concentration angiotensin ii protein level mannose angiotensinogen figure study culture ang i enzyme presence chapter myocyte growth plasma inhibitor system activity result synthesis component intracellular assay mannose 6- phosphate stretch 24 hours danser response experiment schalekamp j bioi chem internalization hypertension angiotensine serum 2 hours minute control uptake circulation cell-associated prorenin schalekamp madh production release cell-associated evidence culture medium hypertrophy angiotensin i renin-angiotensin aug ii renin-angiotensin system increase generation van kesteren rat cardiomyocytes factor ratio measurement losartan renine membrane inhibition huvec