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renin prorenin aliskiren level receptor angiotensin activity binding plasma tissue medium release concentration heart activation study assay figure mast cells control ang i danser effect hypertension generation ang i-generating activity inhibitor angiotensinogen renin release result chapter sample ang ii ang i – prorenin levels tissue sites renin levels antibody blood prorenin binding incubation prosegment protein ang i generation danser ahj culture medium compound detection i-generating prorenin activation 48/80 presence kidney stimulation angiotensin generation measurement amount renin secretory granules renin inhibitor fluid tissue angiotensin generation culture panel minute captopril cell lysates increase granules schalekamp madh organ buffer lysate renine subject percentage conformation stimulation medium system experiment production
8 Most Recent Publications
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Evaluation of a direct prorenin assay making use of a monoclonal antibody directed against residues 32-39 of the prosegment
(Article)
Krop, M. Gool, J.M. van Day, D. Hollenberg, N.K. Danser, A.H.J. |
2011-11-01
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Mast cell degranulation mediates bronchoconstriction via serotonin and not via renin release
(Article)
Krop, M. Özünal, Z.G. Chai, W. Vries, R. de Fekkes, D. Bouhuizen, A.M.B. Garrelds, I.M. Danser, A.H.J. |
2010-08-01
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(Pro)renin Revisited: New Insights from Studies in Mast Cells
(Doctoral Thesis)
Krop, M. |
2009-11-26
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Cardiac renin levels are not influenced by the amount of resident mast cells
(Article)
Krop, M. Veghel, R. van Garrelds, I.M. Bruin, R.J.A. de Gool, J.M. van Meiracker, A.H. van den Thio, M. Daele, P.L.A. van Danser, A.H.J. |
2009-08-01
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Aliskiren accumulates in renin secretory granules and binds plasma prorenin
(Article)
Krop, M. Garrelds, I.M. Bruin, R.J.A. de Gool, J.M. van Fisher, N.D.L. Hollenberg, N.K. Danser, A.H.J. |
2008-12-01
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Prorenin anno 2008
(Article)
Danser, A.H.J. Batenburg, W.W. Esch, J.H.M. van Krop, M. |
2008-06-01
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Circulating versus tissue renin-angiotensin system: On the origin of (Pro)renin
(Article)
Krop, M. Danser, A.H.J. |
2008-04-01
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Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
(Article)
Batenburg, W.W. Krop, M. Garrelds, I.M. Vries, R. de Bruin, R.J.A. de Burckle, C. Müller, D. Bader, M. Nguyen, G. Danser, A.H.J. |
2007-12-01
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