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expression cd 70tg mice patient nucleosome analysis remodeler ifn -␥ brain mct 8 erythroid treatment figure nb-uvb level psoriasis sequence chromatin binding mct 8 patients pathway thalassemia blood protein study group result number hbf levels control table sample nb-uvb therapy effect broblast fi broblasts factor therapy hemoglobin hu treatment erasmu university target material mct 8 expression lesional transcription gene expression pu .1 response klf 1 disease globin adult epidermal erasmus mc differentiation correlation nonlesional skin promoter rotterdam 2 cells erythroid progenitor cells antibody genomic psoriatic anemia dna accessibility hydroxyurea score lesional skin signi nonlesional enrichment remodeler loci histone-dna sequence preferences genetic histone erasmus university rotterdam klf 10 17 pathway
7 Most Recent Publications
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KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in -hemoglobinopathy patients
(Article)
Borg, J. Phylactides, M. Hou, J. Karkabouna, S. Lappa-Manakou, C. Özgür, Z. IJcken, W.F.J. van Lindern, M.M. von Grosveld, F.G. Georgitsi, M. Kleanthous, M. Philipsen, S. Bartsakoulia, M. Patrinos, G.P. Tafrali, C. Lederer, C.W. Felice, A.E. Papachatzopoulou, A. Kourakli, A. Stavrou, E.F. Christou, S. |
2012-10-01
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Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner
(Article)
Moshkin, Y.M. Chalkley, G.E. Kan, T.W. Reddy, B.A. Özgür, Z. IJcken, W.F.J. van Dekkers, D.H. Demmers, J.A. Travers, A.A. Verrijzer, C.P. |
2012-02-01
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Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis
(Article)
Libregts, S.F. Gutiérrez, L. Bruin, A.M. de Wensveen, F.M. Papadopoulos, P. IJcken, W.F.J. van Özgür, Z. Philipsen, S. Nolte, M.A. |
2011-09-01
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Effective treatment of psoriasis with narrow-band UVB phototherapy is linked to suppression of the IFN and Th17 pathways
(Article)
Rácz, E. Prens, E.P. Staal, F.J.T. Fits, L. van der Kurek, D.M. Kant, M. Ridder, D. de Mourits, S. Baerveldt, E.M. Özgür, Z. IJcken, W.F.J. van Laman, J.D. |
2011-07-01
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Transcriptional profiling of fibroblasts from patients with mutations in MCT8 and comparative analysis with the human brain transcriptome
(Article)
Visser, W.E. Swagemakers, S.M.A. Özgür, Z. Schot, R. Verheijen, F.W. IJcken, W.F.J. van Spek, P.J. van der |
2010-08-12
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Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin
(Article)
Borg, J. Papadopoulos, P. Cassar, W. Galdies, R. IJcken, W.F.J. van Özgür, Z. Gillemans, N. Hou, J. Bugeja, M. Grosveld, F.G. Lindern, M.M. von Felice, A.E. Georgitsi, M. Patrinos, G.P. Philipsen, S. Gutiérrez, L. Grech, G. Fanis, P. Phylactides, M. Verkerk, J.H.M. Spek, P.J. van der Scerri, C.A. |
2010-08-01
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Physiological thyroid hormone levels regulate numerous skeletal muscle transcripts
(Article)
Visser, W.E. Heemstra, K.A. Swagemakers, S.M.A. Özgür, Z. Corssmit, E.P. Burggraaf, J. IJcken, W.F.J. van Spek, P.J. van der Smit, J.W.A. Visser, T.J. |
2009-09-01
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