Stein, S.

distance chromatin domain cremer experiment chromosome volume microscopy measurement resolution model pws domains rw /gl model probe nuclei pws domain table compaction fference mls model structure genome signal distance measurements order prader –willi syndrome di fferences precision distance microscopy fferent uorescence chromosome territories confocal interphase chromosome 15 approach genomic light center lymphoblastoid cell nuclei precision region architecture probe pairs organization territory image hausmann broblast chromatin compaction solovei figuration object distribution localization intensity lymphoblastoid identi fied prader limit fication method result syndrome value target nucleus simulation –willi rosettes sequence analysis spdm measurements germany linker column genet 126 kbp loops fl uorescence microscopy hybridization di fference